Insomnia due to drug or substance abuse and dependence

Nicole L. Hadler, Ilana S. Hairston, Deirdre A. Conroy

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Insomnia related to substance abuse, or substance-induced sleep disorder, refers to significant sleep difficulty that is directly associated with active use of or abstinence from a substance. There are numerous prescription and illicit substances that, when abused, can lead to insomnia. This article discusses the substances most commonly implicated in sleep disturbance, including their mechanistic and physiologic effects on sleep, according to the most recent literature. It also highlights potential treatment options for patients with insomnia related to substance abuse.

Original languageEnglish
Title of host publicationEncyclopedia of Sleep and Circadian Rhythms
Subtitle of host publicationVolume 1-6, Second Edition
Number of pages14
ISBN (Electronic)9780323910941
StatePublished - 1 Jan 2023
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2023 Elsevier Inc. All rights reserved


  • Alcohol
  • Benzodiazepine receptor agonists
  • Benzodiazepines
  • Cannabis
  • Cognitive behavioral therapy for insomnia
  • GABA
  • Insomnia
  • Opioids
  • Orexins
  • Sedative-hypnotics
  • Sleep
  • Stimulants

ASJC Scopus subject areas

  • General Neuroscience


Dive into the research topics of 'Insomnia due to drug or substance abuse and dependence'. Together they form a unique fingerprint.

Cite this