Innovation, conservation, and repurposing of gene function in root cell type development

Kaisa Kajala, Mona Gouran, Lidor Shaar-Moshe, G. Alex Mason, Joel Rodriguez-Medina, Dorota Kawa, Germain Pauluzzi, Mauricio Reynoso, Alex Canto-Pastor, Concepcion Manzano, Vincent Lau, Mariana A.S. Artur, Donnelly A. West, Sharon B. Gray, Alexander T. Borowsky, Bryshal P. Moore, Andrew I. Yao, Kevin W. Morimoto, Marko Bajic, Elide FormentinNiba A. Nirmal, Alan Rodriguez, Asher Pasha, Roger B. Deal, Daniel J. Kliebenstein, Torgeir R. Hvidsten, Nicholas J. Provart, Neelima R. Sinha, Daniel E. Runcie, Julia Bailey-Serres, Siobhan M. Brady

Research output: Contribution to journalArticlepeer-review


Plant species have evolved myriads of solutions, including complex cell type development and regulation, to adapt to dynamic environments. To understand this cellular diversity, we profiled tomato root cell type translatomes. Using xylem differentiation in tomato, examples of functional innovation, repurposing, and conservation of transcription factors are described, relative to the model plant Arabidopsis. Repurposing and innovation of genes are further observed within an exodermis regulatory network and illustrate its function. Comparative translatome analyses of rice, tomato, and Arabidopsis cell populations suggest increased expression conservation of root meristems compared with other homologous populations. In addition, the functions of constitutively expressed genes are more conserved than those of cell type/tissue-enriched genes. These observations suggest that higher order properties of cell type and pan-cell type regulation are evolutionarily conserved between plants and animals.

Original languageEnglish
Pages (from-to)3333-3348.e19
Issue number12
StatePublished - 10 Jun 2021
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2021 The Author(s)


  • cell types
  • evolution
  • exodermis
  • gene regulation
  • rice
  • root development
  • tomato
  • translatomes
  • xylem

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology (all)


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