Incidence trends of cervical adenocarcinoma in Israeli Jewish women. A population-based study

Objective. To assess the trend over time of the relative frequency and incidence of adenocarcinoma (AC) in Israeli Jewish women. Design. Register study. Setting. Israel National Cancer Registry. Population. All cases of histologically proven invasive cervical cancer diagnosed during two time periods: 1961-1971 and 2002-2004. Methods. Calculation of frequencies and incidence rates and comparison by the χ2 test and by the Poisson regression model, respectively. Main outcome measures. Frequency and incidence of AC. Results. There were a total of 532 women with a diagnosis of cervical cancer during the first and 434 women during the second period (incidence 4.2 and 4.7/100,000, respectively). The total incidence rates and frequency rates of AC during the two periods were statistically not different. The frequency rate of AC during the second period was significantly higher in the 20-29 and the 40-49 age groups and in the North African born than in the other ethnic groups. Conclusions. Our study indicates that except in certain age and ethnic groups, the frequency and incidence of AC has not significantly altered in Israel over the time periods studied.