Hyperbaric Oxygenation for Necrotizing (Malignant) Otitis Externa

Avi Shupak, Elhanan Greenberg, Ruth Hardoff, Carlos Gordon, Yehuda Melamed, Walter S. Meyer

Research output: Contribution to journalArticlepeer-review


• Two patients with extensive necrotizing otitis externa have been treated by hyperbaric oxygenation. One patient had facial nerve palsy and the other suffered from skull base involvement. Due to severe side effects, the preferred combined intravenous antibiotic therapy was changed to monotherapy in one case and completely withdrawn in the second. This was done before the commencement of hyperbaric oxygenation, while the necrotizing infection was still active. Hyperbaric oxygenation therapy was followed by complete resolution of the necrotizing otitis externa, which did not recur. The pathogenesis of the disease and mechanisms by which hyperbaric oxygenation might be of benefit are described. We conclude that hyperbaric oxygenation should be considered as adjuvant therapy for necrotizing otitis externa whenever a therapeutic pressure chamber is available. (Arch Otolaryngol Head Neck Surg. 1989;115:1470-1475).

Original languageEnglish
Pages (from-to)1470-1475
Number of pages6
JournalJAMA Otolaryngology - Head and Neck Surgery
Issue number12
StatePublished - Dec 1989
Externally publishedYes

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


Dive into the research topics of 'Hyperbaric Oxygenation for Necrotizing (Malignant) Otitis Externa'. Together they form a unique fingerprint.

Cite this