Hemispheric lateralisation and immune function: A systematic review of human research

Rachel C. Sumner; Andrew Parton; Alexander V. Nowicky; Uday Kishore; Yori Gidron

doi:10.1016/j.jneuroim.2011.08.017

Hemispheric lateralisation and immune function: A systematic review of human research

Rachel C. Sumner, Andrew Parton, Alexander V. Nowicky, Uday Kishore, Yori Gidron

Research output: Contribution to journal › Review article › peer-review

Abstract

Past studies examined relationships between hemispheric lateralisation (HL) and immune system functioning. However, there has been no up-dated systematic review of this research area. This article reviews relevant published studies, evaluates study quality and effect sizes. Eleven studies were selected: three revealing a relationship between weaker left hemisphere function and poorer immune function, three describing a relationship between weaker right hemisphere function and stronger immune functioning, and five describing both relationships. Mean effect-size of the studies was r=0.536 (range 0.280-0.866). Collectively, studies point at left-HL and stronger immunity relationships. Limitations, mechanisms and clinical implications are discussed.

Original language	English
Pages (from-to)	1-12
Number of pages	12
Journal	Journal of Neuroimmunology
Volume	240-241
DOIs	https://doi.org/10.1016/j.jneuroim.2011.08.017
State	Published - 15 Dec 2011
Externally published	Yes

Keywords

Brain to immune communication
Diseases
Hemispheric lateralisation
Humans
Immune function
Immunomodulation

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Neurology
Clinical Neurology

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10.1016/j.jneuroim.2011.08.017

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abstract = "Past studies examined relationships between hemispheric lateralisation (HL) and immune system functioning. However, there has been no up-dated systematic review of this research area. This article reviews relevant published studies, evaluates study quality and effect sizes. Eleven studies were selected: three revealing a relationship between weaker left hemisphere function and poorer immune function, three describing a relationship between weaker right hemisphere function and stronger immune functioning, and five describing both relationships. Mean effect-size of the studies was r=0.536 (range 0.280-0.866). Collectively, studies point at left-HL and stronger immunity relationships. Limitations, mechanisms and clinical implications are discussed.",

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AU - Sumner, Rachel C.

AU - Parton, Andrew

AU - Nowicky, Alexander V.

AU - Kishore, Uday

AU - Gidron, Yori

PY - 2011/12/15

Y1 - 2011/12/15

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AB - Past studies examined relationships between hemispheric lateralisation (HL) and immune system functioning. However, there has been no up-dated systematic review of this research area. This article reviews relevant published studies, evaluates study quality and effect sizes. Eleven studies were selected: three revealing a relationship between weaker left hemisphere function and poorer immune function, three describing a relationship between weaker right hemisphere function and stronger immune functioning, and five describing both relationships. Mean effect-size of the studies was r=0.536 (range 0.280-0.866). Collectively, studies point at left-HL and stronger immunity relationships. Limitations, mechanisms and clinical implications are discussed.

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Hemispheric lateralisation and immune function: A systematic review of human research

Abstract

Keywords

ASJC Scopus subject areas

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