Handwriting process variables discriminating mild Alzheimer's disease and mild cognitive impairment

Perla Werner, Sara Rosenblum, Gady Bar-On, Jeremia Heinik, Amos Korczyn

Research output: Contribution to journalArticlepeer-review


This study's aims were (a) to examine kinematically the handwriting process of persons with mild cognitive impairment (MCI), compared with those with mild Alzheimer's disease and healthy controls; (b) to assess the importance of these measures for the differentiation of the groups; and (c) to assess characteristics of the handwriting process across different functional tasks. Thirty-one persons with MCI, 22 with mild Alzheimer's disease, and 41 healthy controls performed functional tasks while using a computerized system. We found significant differences between the groups in almost all measures, with the MCI group assuming a position between the other groups. Temporal measures were higher and pressure was lower in more cognitively deteriorated groups. Information gathered about kinematic measures, together with cognitive functioning, allowed us to classify 69% to 72% of the participants correctly, although the classification for the MCI group was relatively poor.

Original languageEnglish
Pages (from-to)P228-P236
JournalJournals of Gerontology - Series B Psychological Sciences and Social Sciences
Issue number4
StatePublished - Jul 2006

ASJC Scopus subject areas

  • Health(social science)
  • Sociology and Political Science
  • Life-span and Life-course Studies


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