Global and regional burden of disease and injury in 2016 arising from occupational exposures: A systematic analysis for the Global Burden of Disease Study 2016

GBD 2016 Occupational Risk Factors Collaborators

doi:10.1136/oemed-2019-106008

Global and regional burden of disease and injury in 2016 arising from occupational exposures: A systematic analysis for the Global Burden of Disease Study 2016

GBD 2016 Occupational Risk Factors Collaborators

Research output: Contribution to journal › Review article › peer-review

Abstract

Objectives This study provides an overview of the influence of occupational risk factors on the global burden of disease as estimated by the occupational component of the Global Burden of Disease (GBD) 2016 study. Methods The GBD 2016 study estimated the burden in terms of deaths and disability-adjusted life years (DALYs) arising from the effects of occupational risk factors (carcinogens; asthmagens; particulate matter, gases and fumes (PMGF); secondhand smoke (SHS); noise; ergonomic risk factors for low back pain; risk factors for injury). A population attributable fraction (PAF) approach was used for most risk factors. Results In 2016, globally, an estimated 1.53 (95% uncertainty interval 1.39-1.68) million deaths and 76.1 (66.3-86.3) million DALYs were attributable to the included occupational risk factors, accounting for 2.8% of deaths and 3.2% of DALYs from all causes. Most deaths were attributable to PMGF, carcinogens (particularly asbestos), injury risk factors and SHS. Most DALYs were attributable to injury risk factors and ergonomic exposures. Men and persons 55 years or older were most affected. PAFs ranged from 26.8% for low back pain from ergonomic risk factors and 19.6% for hearing loss from noise to 3.4% for carcinogens. DALYs per capita were highest in Oceania, Southeast Asia and Central sub-Saharan Africa. On a per capita basis, between 1990 and 2016 there was an overall decrease of about 31% in deaths and 25% in DALYs. Conclusions Occupational exposures continue to cause an important health burden worldwide, justifying the need for ongoing prevention and control initiatives.

Original language	English
Pages (from-to)	133-141
Number of pages	9
Journal	Occupational and Environmental Medicine
Volume	77
Issue number	3
DOIs	https://doi.org/10.1136/oemed-2019-106008
State	Published - 1 Mar 2020

Bibliographical note

Funding Information:
Acknowledgements BPaQ acknowledges the institutional support of PrOnaBec (national Program of scholarship and educational loan), provided by the Peruvian government; and the Judith lumley centre of la Trobe University. Till Winfried Bärnighausen was supported by the alexander von humboldt Foundation through the alexander von humboldt Professor award, funded by the Federal Ministry of education and research, germany. Félix carvalho acknowledges UiD/ MUlTi/04378/2019 support with funding from FcT/McTes through national funds. eduarda Fernandes acknowledges UiD/QUi/50006/2019 support with funding from FcT/McTes through national funds. Mihajlo Jakovljevic acknowledges that the serbian part of this gBD contribution was cofinanced through grant Oi 175 014 of the Ministry of education, science and Technological Development of the republic of serbia. Yun Jin Kim was supported by the Office of research and innovation, Xiamen University Malaysia. Walter Mendoza is currently a program analyst for Population and Development at the Peru country Office of the United nations Population Fund-UnFPa, an institution which does not necessarily endorse this study. MMolokhia was supported by the national institute for health research (nihr) Biomedical research centre at guy’s and st Thomas’ nhs Foundation Trust and King’s college london. abdallah M samy received a fellowship from the egyptian Fulbright Mission Program (eFMP). sMsi is funded by a senior research Fellowship from the institute for Physical activity and nutrition (iPan), Deakin University. rT-s was supported in part by grant number PrOMeTeOii/2015/021 from generalitat Valenciana and the national grant Pi17/00719 from isciii-FeDer. Paul Yip was supported by the strategic Public Policy research (sPPr) grant (hKU-12).

Funding Information:
Competing interests caTa reports personal fees from Johnson & Johnson (Philippines), outside the submitted work. cc reports personal fees from amgen, Danone, eli lilly, gsK, Kyowa Kirin, Medtronic, Merck, nestle, novartis, Pfizer, roche, servier, shire, Takeda and UcB, outside the submitted work. Bngg reports grants from conselho nacional de Desenvolvimento científico e Tecnológico (cnPq), during the conduct of the study. nK reports personal fees from Junpukai Foundation and softbank; and grants from Fujitsu, Fujitsu software Technologies and softbank, outside the submitted work. JK reports grants from Merck Pharmaceuticals, outside the submitted work. TJM reports grants from cancer Foundation Finland sr, during the conduct of the study.

Funding Information:
Funding The overall gBD study is partly funded by the Bill & Melinda gates Foundation. The work reported in this paper was partly supported by funding from the World health Organization. The funders had no role in the study design, data collection, data analysis, data interpretation or writing of the report. The authors had access to the data in the study and the final responsibility to submit the paper.

Publisher Copyright:
© Author(s) (or their employer(s)) 2020.

Keywords

cancer
ergonomic
noise
respiratory tract diseases
workplace

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1136/oemed-2019-106008

Cite this

@article{59cdd1439c8a42bd9ece9282caeec295,

title = "Global and regional burden of disease and injury in 2016 arising from occupational exposures: A systematic analysis for the Global Burden of Disease Study 2016",

abstract = "Objectives This study provides an overview of the influence of occupational risk factors on the global burden of disease as estimated by the occupational component of the Global Burden of Disease (GBD) 2016 study. Methods The GBD 2016 study estimated the burden in terms of deaths and disability-adjusted life years (DALYs) arising from the effects of occupational risk factors (carcinogens; asthmagens; particulate matter, gases and fumes (PMGF); secondhand smoke (SHS); noise; ergonomic risk factors for low back pain; risk factors for injury). A population attributable fraction (PAF) approach was used for most risk factors. Results In 2016, globally, an estimated 1.53 (95% uncertainty interval 1.39-1.68) million deaths and 76.1 (66.3-86.3) million DALYs were attributable to the included occupational risk factors, accounting for 2.8% of deaths and 3.2% of DALYs from all causes. Most deaths were attributable to PMGF, carcinogens (particularly asbestos), injury risk factors and SHS. Most DALYs were attributable to injury risk factors and ergonomic exposures. Men and persons 55 years or older were most affected. PAFs ranged from 26.8% for low back pain from ergonomic risk factors and 19.6% for hearing loss from noise to 3.4% for carcinogens. DALYs per capita were highest in Oceania, Southeast Asia and Central sub-Saharan Africa. On a per capita basis, between 1990 and 2016 there was an overall decrease of about 31% in deaths and 25% in DALYs. Conclusions Occupational exposures continue to cause an important health burden worldwide, justifying the need for ongoing prevention and control initiatives.",

keywords = "cancer, ergonomic, noise, respiratory tract diseases, workplace",

author = "{GBD 2016 Occupational Risk Factors Collaborators} and Tim Driscoll and Lesley Rushton and Hutchings, {Sally J.} and Kurt Straif and Kyle Steenland and Degu Abate and Cristiana Abbafati and Dilaram Acharya and Adebayo, {Oladimeji M.} and Mahdi Afshari and Tomi Akinyemiju and Fares Alahdab and Mina Anjomshoa and Antonio, {Carl Abelardo T.} and Olatunde Aremu and Zerihun Ataro and AyalaQuintanilla, {Beatriz Paulina} and MattarBanoub, {Joseph Adel} and Barker-Collo, {Suzanne Lyn} and B{\"a}rnighausen, {Till Winfried} and Barrero, {Lope H.} and Neeraj Bedi and Masoud Behzadifar and Meysam Behzadifar and Benavides, {Fernando G.} and Mircea Beuran and Krittika Bhattacharyya and Ali Bijani and Rosario C{\'a}rdenas and Carrero, {Juan J.} and F{\'e}lix Carvalho and Casta{\~n}eda-Orjuela, {Carlos A.} and Ester Cerin and Cyrus Cooper and Lalit Dandona and Rakhi Dandona and Dang, {Anh Kim} and Ahmad Daryani and Desalegn, {Beruk Berhanu} and Dharmaratne, {Samath Dhamminda} and Eleonora Dubljanin and Ziad El-Khatib and Sharareh Eskandarieh and Mohammad Fareed and Andre Faro and Fereshtehnejad, {Seyed Mohammad} and Eduarda Fernandes and Irina Filip and Florian Fischer and Shai Linn",

note = "Funding Information: Acknowledgements BPaQ acknowledges the institutional support of PrOnaBec (national Program of scholarship and educational loan), provided by the Peruvian government; and the Judith lumley centre of la Trobe University. Till Winfried B{\"a}rnighausen was supported by the alexander von humboldt Foundation through the alexander von humboldt Professor award, funded by the Federal Ministry of education and research, germany. F{\'e}lix carvalho acknowledges UiD/ MUlTi/04378/2019 support with funding from FcT/McTes through national funds. eduarda Fernandes acknowledges UiD/QUi/50006/2019 support with funding from FcT/McTes through national funds. Mihajlo Jakovljevic acknowledges that the serbian part of this gBD contribution was cofinanced through grant Oi 175 014 of the Ministry of education, science and Technological Development of the republic of serbia. Yun Jin Kim was supported by the Office of research and innovation, Xiamen University Malaysia. Walter Mendoza is currently a program analyst for Population and Development at the Peru country Office of the United nations Population Fund-UnFPa, an institution which does not necessarily endorse this study. MMolokhia was supported by the national institute for health research (nihr) Biomedical research centre at guy{\textquoteright}s and st Thomas{\textquoteright} nhs Foundation Trust and King{\textquoteright}s college london. abdallah M samy received a fellowship from the egyptian Fulbright Mission Program (eFMP). sMsi is funded by a senior research Fellowship from the institute for Physical activity and nutrition (iPan), Deakin University. rT-s was supported in part by grant number PrOMeTeOii/2015/021 from generalitat Valenciana and the national grant Pi17/00719 from isciii-FeDer. Paul Yip was supported by the strategic Public Policy research (sPPr) grant (hKU-12). Funding Information: Competing interests caTa reports personal fees from Johnson & Johnson (Philippines), outside the submitted work. cc reports personal fees from amgen, Danone, eli lilly, gsK, Kyowa Kirin, Medtronic, Merck, nestle, novartis, Pfizer, roche, servier, shire, Takeda and UcB, outside the submitted work. Bngg reports grants from conselho nacional de Desenvolvimento cient{\'i}fico e Tecnol{\'o}gico (cnPq), during the conduct of the study. nK reports personal fees from Junpukai Foundation and softbank; and grants from Fujitsu, Fujitsu software Technologies and softbank, outside the submitted work. JK reports grants from Merck Pharmaceuticals, outside the submitted work. TJM reports grants from cancer Foundation Finland sr, during the conduct of the study. Funding Information: Funding The overall gBD study is partly funded by the Bill & Melinda gates Foundation. The work reported in this paper was partly supported by funding from the World health Organization. The funders had no role in the study design, data collection, data analysis, data interpretation or writing of the report. The authors had access to the data in the study and the final responsibility to submit the paper. Publisher Copyright: {\textcopyright} Author(s) (or their employer(s)) 2020.",

year = "2020",

month = mar,

day = "1",

doi = "10.1136/oemed-2019-106008",

language = "English",

volume = "77",

pages = "133--141",

journal = "Occupational and Environmental Medicine",

issn = "1351-0711",

publisher = "BMJ Publishing Group",

number = "3",

}

Global and regional burden of disease and injury in 2016 arising from occupational exposures: A systematic analysis for the Global Burden of Disease Study 2016. / GBD 2016 Occupational Risk Factors Collaborators.
In: Occupational and Environmental Medicine, Vol. 77, No. 3, 01.03.2020, p. 133-141.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Global and regional burden of disease and injury in 2016 arising from occupational exposures

T2 - A systematic analysis for the Global Burden of Disease Study 2016

AU - GBD 2016 Occupational Risk Factors Collaborators

AU - Driscoll, Tim

AU - Rushton, Lesley

AU - Hutchings, Sally J.

AU - Straif, Kurt

AU - Steenland, Kyle

AU - Abate, Degu

AU - Abbafati, Cristiana

AU - Acharya, Dilaram

AU - Adebayo, Oladimeji M.

AU - Afshari, Mahdi

AU - Akinyemiju, Tomi

AU - Alahdab, Fares

AU - Anjomshoa, Mina

AU - Antonio, Carl Abelardo T.

AU - Aremu, Olatunde

AU - Ataro, Zerihun

AU - AyalaQuintanilla, Beatriz Paulina

AU - MattarBanoub, Joseph Adel

AU - Barker-Collo, Suzanne Lyn

AU - Bärnighausen, Till Winfried

AU - Barrero, Lope H.

AU - Bedi, Neeraj

AU - Behzadifar, Masoud

AU - Behzadifar, Meysam

AU - Benavides, Fernando G.

AU - Beuran, Mircea

AU - Bhattacharyya, Krittika

AU - Bijani, Ali

AU - Cárdenas, Rosario

AU - Carrero, Juan J.

AU - Carvalho, Félix

AU - Castañeda-Orjuela, Carlos A.

AU - Cerin, Ester

AU - Cooper, Cyrus

AU - Dandona, Lalit

AU - Dandona, Rakhi

AU - Dang, Anh Kim

AU - Daryani, Ahmad

AU - Desalegn, Beruk Berhanu

AU - Dharmaratne, Samath Dhamminda

AU - Dubljanin, Eleonora

AU - El-Khatib, Ziad

AU - Eskandarieh, Sharareh

AU - Fareed, Mohammad

AU - Faro, Andre

AU - Fereshtehnejad, Seyed Mohammad

AU - Fernandes, Eduarda

AU - Filip, Irina

AU - Fischer, Florian

AU - Linn, Shai

N1 - Funding Information: Acknowledgements BPaQ acknowledges the institutional support of PrOnaBec (national Program of scholarship and educational loan), provided by the Peruvian government; and the Judith lumley centre of la Trobe University. Till Winfried Bärnighausen was supported by the alexander von humboldt Foundation through the alexander von humboldt Professor award, funded by the Federal Ministry of education and research, germany. Félix carvalho acknowledges UiD/ MUlTi/04378/2019 support with funding from FcT/McTes through national funds. eduarda Fernandes acknowledges UiD/QUi/50006/2019 support with funding from FcT/McTes through national funds. Mihajlo Jakovljevic acknowledges that the serbian part of this gBD contribution was cofinanced through grant Oi 175 014 of the Ministry of education, science and Technological Development of the republic of serbia. Yun Jin Kim was supported by the Office of research and innovation, Xiamen University Malaysia. Walter Mendoza is currently a program analyst for Population and Development at the Peru country Office of the United nations Population Fund-UnFPa, an institution which does not necessarily endorse this study. MMolokhia was supported by the national institute for health research (nihr) Biomedical research centre at guy’s and st Thomas’ nhs Foundation Trust and King’s college london. abdallah M samy received a fellowship from the egyptian Fulbright Mission Program (eFMP). sMsi is funded by a senior research Fellowship from the institute for Physical activity and nutrition (iPan), Deakin University. rT-s was supported in part by grant number PrOMeTeOii/2015/021 from generalitat Valenciana and the national grant Pi17/00719 from isciii-FeDer. Paul Yip was supported by the strategic Public Policy research (sPPr) grant (hKU-12). Funding Information: Competing interests caTa reports personal fees from Johnson & Johnson (Philippines), outside the submitted work. cc reports personal fees from amgen, Danone, eli lilly, gsK, Kyowa Kirin, Medtronic, Merck, nestle, novartis, Pfizer, roche, servier, shire, Takeda and UcB, outside the submitted work. Bngg reports grants from conselho nacional de Desenvolvimento científico e Tecnológico (cnPq), during the conduct of the study. nK reports personal fees from Junpukai Foundation and softbank; and grants from Fujitsu, Fujitsu software Technologies and softbank, outside the submitted work. JK reports grants from Merck Pharmaceuticals, outside the submitted work. TJM reports grants from cancer Foundation Finland sr, during the conduct of the study. Funding Information: Funding The overall gBD study is partly funded by the Bill & Melinda gates Foundation. The work reported in this paper was partly supported by funding from the World health Organization. The funders had no role in the study design, data collection, data analysis, data interpretation or writing of the report. The authors had access to the data in the study and the final responsibility to submit the paper. Publisher Copyright: © Author(s) (or their employer(s)) 2020.

PY - 2020/3/1

Y1 - 2020/3/1

N2 - Objectives This study provides an overview of the influence of occupational risk factors on the global burden of disease as estimated by the occupational component of the Global Burden of Disease (GBD) 2016 study. Methods The GBD 2016 study estimated the burden in terms of deaths and disability-adjusted life years (DALYs) arising from the effects of occupational risk factors (carcinogens; asthmagens; particulate matter, gases and fumes (PMGF); secondhand smoke (SHS); noise; ergonomic risk factors for low back pain; risk factors for injury). A population attributable fraction (PAF) approach was used for most risk factors. Results In 2016, globally, an estimated 1.53 (95% uncertainty interval 1.39-1.68) million deaths and 76.1 (66.3-86.3) million DALYs were attributable to the included occupational risk factors, accounting for 2.8% of deaths and 3.2% of DALYs from all causes. Most deaths were attributable to PMGF, carcinogens (particularly asbestos), injury risk factors and SHS. Most DALYs were attributable to injury risk factors and ergonomic exposures. Men and persons 55 years or older were most affected. PAFs ranged from 26.8% for low back pain from ergonomic risk factors and 19.6% for hearing loss from noise to 3.4% for carcinogens. DALYs per capita were highest in Oceania, Southeast Asia and Central sub-Saharan Africa. On a per capita basis, between 1990 and 2016 there was an overall decrease of about 31% in deaths and 25% in DALYs. Conclusions Occupational exposures continue to cause an important health burden worldwide, justifying the need for ongoing prevention and control initiatives.

AB - Objectives This study provides an overview of the influence of occupational risk factors on the global burden of disease as estimated by the occupational component of the Global Burden of Disease (GBD) 2016 study. Methods The GBD 2016 study estimated the burden in terms of deaths and disability-adjusted life years (DALYs) arising from the effects of occupational risk factors (carcinogens; asthmagens; particulate matter, gases and fumes (PMGF); secondhand smoke (SHS); noise; ergonomic risk factors for low back pain; risk factors for injury). A population attributable fraction (PAF) approach was used for most risk factors. Results In 2016, globally, an estimated 1.53 (95% uncertainty interval 1.39-1.68) million deaths and 76.1 (66.3-86.3) million DALYs were attributable to the included occupational risk factors, accounting for 2.8% of deaths and 3.2% of DALYs from all causes. Most deaths were attributable to PMGF, carcinogens (particularly asbestos), injury risk factors and SHS. Most DALYs were attributable to injury risk factors and ergonomic exposures. Men and persons 55 years or older were most affected. PAFs ranged from 26.8% for low back pain from ergonomic risk factors and 19.6% for hearing loss from noise to 3.4% for carcinogens. DALYs per capita were highest in Oceania, Southeast Asia and Central sub-Saharan Africa. On a per capita basis, between 1990 and 2016 there was an overall decrease of about 31% in deaths and 25% in DALYs. Conclusions Occupational exposures continue to cause an important health burden worldwide, justifying the need for ongoing prevention and control initiatives.

KW - cancer

KW - ergonomic

KW - noise

KW - respiratory tract diseases

KW - workplace

UR - http://www.scopus.com/inward/record.url?scp=85079338010&partnerID=8YFLogxK

U2 - 10.1136/oemed-2019-106008

DO - 10.1136/oemed-2019-106008

M3 - Review article

C2 - 32054817

AN - SCOPUS:85079338010

SN - 1351-0711

VL - 77

SP - 133

EP - 141

JO - Occupational and Environmental Medicine

JF - Occupational and Environmental Medicine

IS - 3

ER -

Global and regional burden of disease and injury in 2016 arising from occupational exposures: A systematic analysis for the Global Burden of Disease Study 2016

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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