Genetic polymorphism of urine deoxyribonuclease I isomerases of subterranean mole rats, Spalax ehrenbergi superspecies, in Israel: Ecogeographical patterns and correlates

Eviatar Nevo, Koichiro Kishi, Avigdor Beiles

Research output: Contribution to journalArticlepeer-review

Abstract

Genetic polymorphism of urine deoxyribonuclease I (DNase I) of mole rats was analyzed by isoelectric focusing in a thin-layer polyacrylamide gel (IEF-PAGE). One hundred and three subterranean mole rats, comprising 13 populations belonging to the four chromosomal species (2 n = 52, 54, 58, 60) of the actively speciating Spalax ehrenbergi superspecies in Israel, were tested. The following results were indicated. (i)Spalax DNase I consisted of 6-12 major isozymes. (ii) Four phenotypes (numbers in parentheses) were 1 (92), 1-2 (5), 1-3 (4), and 2 (1). The decreasing order of genetic diversity, He, in the four species was 0.37, 0.13, 0.10, and 0.0 for 2 n = 58, 52, 54, and 60, respectively. (iii) Spearman rank correlations and multiple regression analyses indicated associations of allele frequencies and genetic diversity with climatic and vegetation factors. We concluded that (a) climatic selection, either directly or indirectly through plant (i.e., food resources) diversity, plays an important role in DNase genetic differentiation and (b) no gene flow and introgression occur between the recent derivative of speciation (2 n = 60) and its ancestor (2 n = 58), suggesting the operation of reproductive isolation between both species despite natural hybridization.

Original languageEnglish
Pages (from-to)561-570
Number of pages10
JournalBiochemical Genetics
Volume28
Issue number11-12
DOIs
StatePublished - Dec 1990

Keywords

  • Spalax ehrenbergi
  • deoxyribonuclease (DNase)
  • genetic polymorphism
  • isozymes
  • natural selection
  • subterranean mammals

ASJC Scopus subject areas

  • Genetics
  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Biochemistry

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