Genes and Genomic Searches

C. P. Kyriacou; E. Tauber

doi:10.1016/B978-0-08-045337-8.00166-2

Genes and Genomic Searches

C. P. Kyriacou, E. Tauber

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The genetic analysis of behavior has a long history, yet it is only 25 years since the first ‘behavioral’ genes were identified at the molecular level. These advances were based on prior genomic screens involving random chemical mutagenesis, initially in the fruitfly Drosophila melanogaster and then later in the mouse. Several ‘forward genetic’ techniques now exist to complement this basic approach, but ‘reverse genetics,’ whereby DNA or mRNA can be identified, targeted, and manipulated, can also be utilized to create mutant phenotypes. We provide some examples of the successes of these approaches involving circadian rhythms, sexual behavior, and aggression.

Original language	English
Title of host publication	Encyclopedia of Animal Behavior, Volume-Three Set
Publisher	Elsevier
Pages	V2-12-V2-20
Volume	2
ISBN (Electronic)	9780080453378
ISBN (Print)	9780080453330
DOIs	https://doi.org/10.1016/B978-0-08-045337-8.00166-2
State	Published - 1 Jan 2010
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2010 Elsevier Ltd. All rights reserved.

Keywords

Aggression
Circadian
Courtship
Epigenetics
Genetics
Genomics
Linkage
Maternal
Microarray
Mutagenesis
Phenotype
QTL
RNAi
Schizophrenia
Transcriptomics

ASJC Scopus subject areas

General Agricultural and Biological Sciences

Access to Document

10.1016/B978-0-08-045337-8.00166-2

Cite this

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KW - Circadian

KW - Courtship

KW - Epigenetics

KW - Genetics

KW - Genomics

KW - Linkage

KW - Maternal

KW - Microarray

KW - Mutagenesis

KW - Phenotype

KW - QTL

KW - RNAi

KW - Schizophrenia

KW - Transcriptomics

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SN - 9780080453330

VL - 2

SP - V2-12-V2-20

BT - Encyclopedia of Animal Behavior, Volume-Three Set

PB - Elsevier

ER -

Genes and Genomic Searches

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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