Functional Magnetic Resonance Imaging: Design and Analysis

Pia Rotshtein, Charumati Raghavan

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


This article is a basic introduction to design and analysis for functional Magnetic Resonance Imaging (fMRI) studies. The article describes the fMRI experimental set up and commonly used spatial and temporal data pre-processing steps. It then describes a typical study design, differentiating between task-based and resting-state fMRI. It is followed by a brief description of statistical analysis techniques used to draw inferences, including univariate and multivariate approaches. At the end, most common software used to analysis fMRI data are listed.

Original languageEnglish
Title of host publicationEncyclopedia of Behavioral Neuroscience
Subtitle of host publicationVolumes 1-3, Second edition
ISBN (Electronic)9780128196410
StatePublished - 1 Jan 2021
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Ltd. All rights reserved.


  • 1st level analysis
  • 2nd level analysis
  • MNI space
  • Mass univariate analysis
  • Motion correction
  • Multivariate analysis
  • Normalisation
  • Talairach space

ASJC Scopus subject areas

  • General Medicine
  • General Neuroscience


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