Evidence for weight management by nutrition for the progression of NAFLD, metabolic or cardiovascular disease

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

• Lifestyle change, including dietary habits and physical activity, is the first-line treatment in
NAFLD and NASH.
• Weight reduction via diet has the most established effect on regression of steatosis, fibrosis
and resolution of NASH, with a clear dose-response association.
• Any generally healthy diet (low fat or low carb or Mediterranean), tailored to the patient’s
health status, which will lead to caloric reduction and is acceptable by the patient, can be
used.
• Changing dietary composition without necessarily reducing caloric intake may promote
maintenance of weight reduction and liver steaatosis reducation in the long-term, and may
represent a more feasible alternative to treat NAFLD patients.
• Recent feeding studies and short-term clinical trials emphasised the independent therapeutic
effect of replacing an unhealthy Western dietary pattern, typical to NAFLD patients, with a
healthy pattern (e.g. Mediterranean diet).
• A heathy lifestyle is also important in terms of glycaemic control and primary prevention of
CVD and HCC.
Original languageEnglish
Title of host publicationEuropean Association for the Study of the Liver postgraduate course international liver congress book
PublisherEuropean Association for the Study of the Liver postgraduate course international liver congress
Pages150-157
Number of pages8
StatePublished - 2017
EventThe International Liver Congress: A multidisciplinary approach to patients with liver disease - Amsterdam, Netherlands
Duration: 19 Apr 201720 Apr 2017

Conference

ConferenceThe International Liver Congress
Country/TerritoryNetherlands
CityAmsterdam
Period19/04/1720/04/17

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