Evaluating functional decline in patients with Multiple Sclerosis

Sara Rosenblum; Patrice L. (Tamar) Weiss

doi:10.1016/j.ridd.2009.12.008

Evaluating functional decline in patients with Multiple Sclerosis

Sara Rosenblum, Patrice L. (Tamar) Weiss

Department of Occupational Therapy

Research output: Contribution to journal › Article › peer-review

Abstract

Multiple Sclerosis (MS) is a disease with a wide-ranging impact on functional status. The aim of the study was to examine the added value of simultaneously evaluating fatigue, personal ADL and handwriting performance as indicators for functional decline among patients with MS. Participants were 50 outpatients with MS and 26 matched healthy controls. Data collection instruments included a disability status scale, the Fatigue Severity Scale (FSS), and the Physical Self-Maintenance Scale (PSMS). Handwriting performance was evaluated by objective computerized measures of the handwriting process (ComPET). Significant differences were found between patients with MS and control subjects in their fatigue level, their PSMS score and In-air time per stroke while writing. The FSS together with specific PSMS items and handwriting measures achieved correct classification of 87.7% of the participants. These results are the first step towards demonstrating the added value of evaluating body function outcomes (fatigue) together with activity performance (handwriting and ADL) to document functional decline among patients with MS. These results may contribute to the development of practical intervention strategies targeted at improving performance abilities among patients with MS.

Original language	English
Pages (from-to)	577-586
Number of pages	10
Journal	Research in Developmental Disabilities
Volume	31
Issue number	2
DOIs	https://doi.org/10.1016/j.ridd.2009.12.008
State	Published - Mar 2010

Bibliographical note

Funding Information:
The authors would like to thank Ariel Miller, MD, PhD from the Department of Neurology, Carmel Medical Center, Haifa 34362, Israel, for his valuable contribution to patient selection and diagnosis. The authors are grateful to the Israeli Science Foundation (Academia) for financial support. We also thank and appreciate Liat Lachter for her assistance with the research process.

Keywords

Fatigue
Handwriting
Personal activities of daily living

ASJC Scopus subject areas

Developmental and Educational Psychology
Clinical Psychology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ridd.2009.12.008

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title = "Evaluating functional decline in patients with Multiple Sclerosis",

abstract = "Multiple Sclerosis (MS) is a disease with a wide-ranging impact on functional status. The aim of the study was to examine the added value of simultaneously evaluating fatigue, personal ADL and handwriting performance as indicators for functional decline among patients with MS. Participants were 50 outpatients with MS and 26 matched healthy controls. Data collection instruments included a disability status scale, the Fatigue Severity Scale (FSS), and the Physical Self-Maintenance Scale (PSMS). Handwriting performance was evaluated by objective computerized measures of the handwriting process (ComPET). Significant differences were found between patients with MS and control subjects in their fatigue level, their PSMS score and In-air time per stroke while writing. The FSS together with specific PSMS items and handwriting measures achieved correct classification of 87.7% of the participants. These results are the first step towards demonstrating the added value of evaluating body function outcomes (fatigue) together with activity performance (handwriting and ADL) to document functional decline among patients with MS. These results may contribute to the development of practical intervention strategies targeted at improving performance abilities among patients with MS.",

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author = "Sara Rosenblum and {(Tamar) Weiss}, {Patrice L.}",

note = "Funding Information: The authors would like to thank Ariel Miller, MD, PhD from the Department of Neurology, Carmel Medical Center, Haifa 34362, Israel, for his valuable contribution to patient selection and diagnosis. The authors are grateful to the Israeli Science Foundation (Academia) for financial support. We also thank and appreciate Liat Lachter for her assistance with the research process.",

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N2 - Multiple Sclerosis (MS) is a disease with a wide-ranging impact on functional status. The aim of the study was to examine the added value of simultaneously evaluating fatigue, personal ADL and handwriting performance as indicators for functional decline among patients with MS. Participants were 50 outpatients with MS and 26 matched healthy controls. Data collection instruments included a disability status scale, the Fatigue Severity Scale (FSS), and the Physical Self-Maintenance Scale (PSMS). Handwriting performance was evaluated by objective computerized measures of the handwriting process (ComPET). Significant differences were found between patients with MS and control subjects in their fatigue level, their PSMS score and In-air time per stroke while writing. The FSS together with specific PSMS items and handwriting measures achieved correct classification of 87.7% of the participants. These results are the first step towards demonstrating the added value of evaluating body function outcomes (fatigue) together with activity performance (handwriting and ADL) to document functional decline among patients with MS. These results may contribute to the development of practical intervention strategies targeted at improving performance abilities among patients with MS.

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Evaluating functional decline in patients with Multiple Sclerosis

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

UN SDGs

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