Enantio- and diastereoselective tandem zn-promoted brook rearrangement/ene - Allene carbocyclization reaction

Rozalia Linger; Fritz Weisser; Nicka Chinkov; Amnon Stanger; Theodore Cohen; Han Marek

doi:10.1021/ol9004036

Enantio- and diastereoselective tandem zn-promoted brook rearrangement/ene - Allene carbocyclization reaction

Rozalia Linger, Fritz Weisser, Nicka Chinkov, Amnon Stanger, Theodore Cohen, Han Marek

Research output: Contribution to journal › Article › peer-review

Abstract

The zinc-catalyzed addition of various alkynes to acylsilanes followed by a Zn- Brook rearrangement and either the Zn- ene- allene or Zn- yne- allene cyclization led to the enantio- and diastereoselective formation of carbocycles in a single-pot operation.

Original language	English
Pages (from-to)	1852-1855
Number of pages	4
Journal	Organic Letters
Volume	11
Issue number	8
DOIs	https://doi.org/10.1021/ol9004036
State	Published - 16 Apr 2009
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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10.1021/ol9004036

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title = "Enantio- and diastereoselective tandem zn-promoted brook rearrangement/ene - Allene carbocyclization reaction",

abstract = "The zinc-catalyzed addition of various alkynes to acylsilanes followed by a Zn- Brook rearrangement and either the Zn- ene- allene or Zn- yne- allene cyclization led to the enantio- and diastereoselective formation of carbocycles in a single-pot operation.",

author = "Rozalia Linger and Fritz Weisser and Nicka Chinkov and Amnon Stanger and Theodore Cohen and Han Marek",

year = "2009",

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AU - Linger, Rozalia

AU - Weisser, Fritz

AU - Chinkov, Nicka

AU - Stanger, Amnon

AU - Cohen, Theodore

AU - Marek, Han

PY - 2009/4/16

Y1 - 2009/4/16

N2 - The zinc-catalyzed addition of various alkynes to acylsilanes followed by a Zn- Brook rearrangement and either the Zn- ene- allene or Zn- yne- allene cyclization led to the enantio- and diastereoselective formation of carbocycles in a single-pot operation.

AB - The zinc-catalyzed addition of various alkynes to acylsilanes followed by a Zn- Brook rearrangement and either the Zn- ene- allene or Zn- yne- allene cyclization led to the enantio- and diastereoselective formation of carbocycles in a single-pot operation.

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U2 - 10.1021/ol9004036

DO - 10.1021/ol9004036

M3 - Article

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AN - SCOPUS:65249088073

SN - 1523-7060

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SP - 1852

EP - 1855

JO - Organic Letters

JF - Organic Letters

IS - 8

ER -

Enantio- and diastereoselective tandem zn-promoted brook rearrangement/ene - Allene carbocyclization reaction

Abstract

ASJC Scopus subject areas

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