The histological and structural features of Bitot's spots are described. Light microscopy revealed squamous metaplasia with keratinization. Electron microscopy showed severe loss and attenuation in height of microvilli as well as widening of the intercellular spaces. The amorphous material overlying the conjunctiva was composed of cellular debris containing edemetous endoplasmic reticular membranes and lysozomes.
|Number of pages||3|
|Journal||Metabolic, Pediatric and Systemic Ophthalmology|
|State||Published - 1987|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Endocrinology, Diabetes and Metabolism