Effects of Δ1(2)-tetrahydrocannabinol on copulation in the male rat

Ariel Merari; Azy Barak; Moshe Plaves

doi:10.1007/BF00429304

Effects of Δ¹⁽²⁾-tetrahydrocannabinol on copulation in the male rat

Ariel Merari, Azy Barak, Moshe Plaves

Research output: Contribution to journal › Article › peer-review

Abstract

The mating behavior of 15 male rats was measured after treatment with δ¹⁽²⁾-tetrahydrocannabinol (THC) and propylene glycol (vehicle). Administration of either 2 mg per kg or 3 mg per kg body weight of THC was followed by significant increases in latency to the first mount, latency to ejaculation, and latency to the first mount following ejaculation. No significant changes were found in the number of intromissions or mounts. The deterioration in sexual performance is interpreted as reflecting a decreased motivation to copulate under the influence of the drug.

Original language	English
Pages (from-to)	243-246
Number of pages	4
Journal	Psychopharmacology
Volume	28
Issue number	3
DOIs	https://doi.org/10.1007/BF00429304
State	Published - Sep 1973
Externally published	Yes

Keywords

Copulation
Rat
δ-THC

ASJC Scopus subject areas

Pharmacology

Access to Document

10.1007/BF00429304

Cite this

@article{4eb7ece068b849b9a2b47a7669d26d9d,

title = "Effects of Δ1(2)-tetrahydrocannabinol on copulation in the male rat",

abstract = "The mating behavior of 15 male rats was measured after treatment with δ1(2)-tetrahydrocannabinol (THC) and propylene glycol (vehicle). Administration of either 2 mg per kg or 3 mg per kg body weight of THC was followed by significant increases in latency to the first mount, latency to ejaculation, and latency to the first mount following ejaculation. No significant changes were found in the number of intromissions or mounts. The deterioration in sexual performance is interpreted as reflecting a decreased motivation to copulate under the influence of the drug.",

keywords = "Copulation, Rat, δ-THC",

author = "Ariel Merari and Azy Barak and Moshe Plaves",

year = "1973",

month = sep,

doi = "10.1007/BF00429304",

language = "English",

volume = "28",

pages = "243--246",

journal = "Psychopharmacology",

issn = "0033-3158",

publisher = "Springer Verlag",

number = "3",

}

TY - JOUR

T1 - Effects of Δ1(2)-tetrahydrocannabinol on copulation in the male rat

AU - Merari, Ariel

AU - Barak, Azy

AU - Plaves, Moshe

PY - 1973/9

Y1 - 1973/9

N2 - The mating behavior of 15 male rats was measured after treatment with δ1(2)-tetrahydrocannabinol (THC) and propylene glycol (vehicle). Administration of either 2 mg per kg or 3 mg per kg body weight of THC was followed by significant increases in latency to the first mount, latency to ejaculation, and latency to the first mount following ejaculation. No significant changes were found in the number of intromissions or mounts. The deterioration in sexual performance is interpreted as reflecting a decreased motivation to copulate under the influence of the drug.

AB - The mating behavior of 15 male rats was measured after treatment with δ1(2)-tetrahydrocannabinol (THC) and propylene glycol (vehicle). Administration of either 2 mg per kg or 3 mg per kg body weight of THC was followed by significant increases in latency to the first mount, latency to ejaculation, and latency to the first mount following ejaculation. No significant changes were found in the number of intromissions or mounts. The deterioration in sexual performance is interpreted as reflecting a decreased motivation to copulate under the influence of the drug.

KW - Copulation

KW - Rat

KW - δ-THC

UR - http://www.scopus.com/inward/record.url?scp=0015541064&partnerID=8YFLogxK

U2 - 10.1007/BF00429304

DO - 10.1007/BF00429304

M3 - Article

C2 - 4690999

AN - SCOPUS:0015541064

SN - 0033-3158

VL - 28

SP - 243

EP - 246

JO - Psychopharmacology

JF - Psychopharmacology

IS - 3

ER -