Effects of Δ1(2)-tetrahydrocannabinol on copulation in the male rat

Ariel Merari, Azy Barak, Moshe Plaves

Research output: Contribution to journalArticlepeer-review


The mating behavior of 15 male rats was measured after treatment with δ1(2)-tetrahydrocannabinol (THC) and propylene glycol (vehicle). Administration of either 2 mg per kg or 3 mg per kg body weight of THC was followed by significant increases in latency to the first mount, latency to ejaculation, and latency to the first mount following ejaculation. No significant changes were found in the number of intromissions or mounts. The deterioration in sexual performance is interpreted as reflecting a decreased motivation to copulate under the influence of the drug.

Original languageEnglish
Pages (from-to)243-246
Number of pages4
Issue number3
StatePublished - Sep 1973
Externally publishedYes


  • Copulation
  • Rat
  • δ-THC

ASJC Scopus subject areas

  • Pharmacology


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