EASL Clinical Practice Guidelines on nutrition in chronic liver disease

European Association for the Study of the Liver

doi:10.1016/j.jhep.2018.06.024

EASL Clinical Practice Guidelines on nutrition in chronic liver disease

European Association for the Study of the Liver

School of Public Health

Research output: Contribution to journal › Article › peer-review

Abstract

A frequent complication in liver cirrhosis is malnutrition, which is associated with the progression of liver failure, and with a higher rate of complications including infections, hepatic encephalopathy and ascites. In recent years, the rising prevalence of obesity has led to an increase in the number of cirrhosis cases related to non-alcoholic steatohepatitis. Malnutrition, obesity and sarcopenic obesity may worsen the prognosis of patients with liver cirrhosis and lower their survival. Nutritional monitoring and intervention is therefore crucial in chronic liver disease. These Clinical Practice Guidelines review the present knowledge in the field of nutrition in chronic liver disease and promote further research on this topic. Screening, assessment and principles of nutritional management are examined, with recommendations provided in specific settings such as hepatic encephalopathy, cirrhotic patients with bone disease, patients undergoing liver surgery or transplantation and critically ill cirrhotic patients.

Original language	English
Pages (from-to)	172-193
Number of pages	22
Journal	Journal of Hepatology
Volume	70
Issue number	1
DOIs	https://doi.org/10.1016/j.jhep.2018.06.024
State	Published - Jan 2019

Bibliographical note

Funding Information:
S.D. reports grant/research support from the National Institutes of Health, RO1 DK113196; RO1 GM 119174; R21 AR071045; P50 AA024333; UO1 AA021890; UO1061732 and the Mikati Foundation Research Grant. A.P. reports grants, personal fees and other from Intercept Pharmaceuticals, other from Novartis, personal fees from Cymabay Therapeutics, Inc., outside the submitted work. M.M. reports personal fees from Kedrion. All other authors report no conflicts of interest.

Funding Information:
S.D. reports grant/research support from the National Institutes of Health , RO1 DK113196; RO1 GM 119174; R21 AR071045; P50 AA024333; UO1 AA021890; UO1061732 and the Mikati Foundation Research Grant. A.P. reports grants, personal fees and other from Intercept Pharmaceuticals, other from Novartis, personal fees from Cymabay Therapeutics, Inc., outside the submitted work. M.M. reports personal fees from Kedrion. All other authors report no conflicts of interest.

Publisher Copyright:
© 2018 European Association for the Study of the Liver

ASJC Scopus subject areas

Hepatology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jhep.2018.06.024

Cite this

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title = "EASL Clinical Practice Guidelines on nutrition in chronic liver disease",

abstract = "A frequent complication in liver cirrhosis is malnutrition, which is associated with the progression of liver failure, and with a higher rate of complications including infections, hepatic encephalopathy and ascites. In recent years, the rising prevalence of obesity has led to an increase in the number of cirrhosis cases related to non-alcoholic steatohepatitis. Malnutrition, obesity and sarcopenic obesity may worsen the prognosis of patients with liver cirrhosis and lower their survival. Nutritional monitoring and intervention is therefore crucial in chronic liver disease. These Clinical Practice Guidelines review the present knowledge in the field of nutrition in chronic liver disease and promote further research on this topic. Screening, assessment and principles of nutritional management are examined, with recommendations provided in specific settings such as hepatic encephalopathy, cirrhotic patients with bone disease, patients undergoing liver surgery or transplantation and critically ill cirrhotic patients.",

author = "{European Association for the Study of the Liver} and Manuela Merli and Annalisa Berzigotti and Shira Zelber-Sagi and Srinivasan Dasarathy and Sara Montagnese and Laurence Genton and Mathias Plauth and Albert Par{\'e}s",

note = "Funding Information: S.D. reports grant/research support from the National Institutes of Health, RO1 DK113196; RO1 GM 119174; R21 AR071045; P50 AA024333; UO1 AA021890; UO1061732 and the Mikati Foundation Research Grant. A.P. reports grants, personal fees and other from Intercept Pharmaceuticals, other from Novartis, personal fees from Cymabay Therapeutics, Inc., outside the submitted work. M.M. reports personal fees from Kedrion. All other authors report no conflicts of interest. Funding Information: S.D. reports grant/research support from the National Institutes of Health , RO1 DK113196; RO1 GM 119174; R21 AR071045; P50 AA024333; UO1 AA021890; UO1061732 and the Mikati Foundation Research Grant. A.P. reports grants, personal fees and other from Intercept Pharmaceuticals, other from Novartis, personal fees from Cymabay Therapeutics, Inc., outside the submitted work. M.M. reports personal fees from Kedrion. All other authors report no conflicts of interest. Publisher Copyright: {\textcopyright} 2018 European Association for the Study of the Liver",

year = "2019",

month = jan,

doi = "10.1016/j.jhep.2018.06.024",

language = "English",

volume = "70",

pages = "172--193",

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AU - Merli, Manuela

AU - Berzigotti, Annalisa

AU - Zelber-Sagi, Shira

AU - Dasarathy, Srinivasan

AU - Montagnese, Sara

AU - Genton, Laurence

AU - Plauth, Mathias

AU - Parés, Albert

N1 - Funding Information: S.D. reports grant/research support from the National Institutes of Health, RO1 DK113196; RO1 GM 119174; R21 AR071045; P50 AA024333; UO1 AA021890; UO1061732 and the Mikati Foundation Research Grant. A.P. reports grants, personal fees and other from Intercept Pharmaceuticals, other from Novartis, personal fees from Cymabay Therapeutics, Inc., outside the submitted work. M.M. reports personal fees from Kedrion. All other authors report no conflicts of interest. Funding Information: S.D. reports grant/research support from the National Institutes of Health , RO1 DK113196; RO1 GM 119174; R21 AR071045; P50 AA024333; UO1 AA021890; UO1061732 and the Mikati Foundation Research Grant. A.P. reports grants, personal fees and other from Intercept Pharmaceuticals, other from Novartis, personal fees from Cymabay Therapeutics, Inc., outside the submitted work. M.M. reports personal fees from Kedrion. All other authors report no conflicts of interest. Publisher Copyright: © 2018 European Association for the Study of the Liver

PY - 2019/1

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N2 - A frequent complication in liver cirrhosis is malnutrition, which is associated with the progression of liver failure, and with a higher rate of complications including infections, hepatic encephalopathy and ascites. In recent years, the rising prevalence of obesity has led to an increase in the number of cirrhosis cases related to non-alcoholic steatohepatitis. Malnutrition, obesity and sarcopenic obesity may worsen the prognosis of patients with liver cirrhosis and lower their survival. Nutritional monitoring and intervention is therefore crucial in chronic liver disease. These Clinical Practice Guidelines review the present knowledge in the field of nutrition in chronic liver disease and promote further research on this topic. Screening, assessment and principles of nutritional management are examined, with recommendations provided in specific settings such as hepatic encephalopathy, cirrhotic patients with bone disease, patients undergoing liver surgery or transplantation and critically ill cirrhotic patients.

AB - A frequent complication in liver cirrhosis is malnutrition, which is associated with the progression of liver failure, and with a higher rate of complications including infections, hepatic encephalopathy and ascites. In recent years, the rising prevalence of obesity has led to an increase in the number of cirrhosis cases related to non-alcoholic steatohepatitis. Malnutrition, obesity and sarcopenic obesity may worsen the prognosis of patients with liver cirrhosis and lower their survival. Nutritional monitoring and intervention is therefore crucial in chronic liver disease. These Clinical Practice Guidelines review the present knowledge in the field of nutrition in chronic liver disease and promote further research on this topic. Screening, assessment and principles of nutritional management are examined, with recommendations provided in specific settings such as hepatic encephalopathy, cirrhotic patients with bone disease, patients undergoing liver surgery or transplantation and critically ill cirrhotic patients.

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EASL Clinical Practice Guidelines on nutrition in chronic liver disease

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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