TY - JOUR
T1 - Does the modern urbanized sleeping habitat pose a breast cancer risk?
AU - Kloog, Itai
AU - Portnov, Boris A.
AU - Rennert, Hedy S.
AU - Haim, Abraham
PY - 2011/2
Y1 - 2011/2
N2 - Due to its disruptive effects on circadian rhythms and sleep deprivation at night, shiftworking is currently recognized as a risk factor for breast cancer (BC). As revealed by the present analysis based on a comparative case-control study of 1679 women, exposure to light-at-night (LAN) in the "sleeping habitat" is significantly associated with BC risk (odds ratio [OR]=1.220, 95% confidence interval [CI]=1.118-1.311; p<.001), controlling for education, ethnicity, fertility, and alcohol consumption. The novelty of the present research is that, to the best of the authors' knowledge, it is the first study to have identified an unequivocal positive association between bedroom-light intensity and BC risk. Thus, according to the results of the present study, not only should artificial light exposure in the working environment be considered as a potential risk factor for BC, but also LAN in the "sleeping habitat."
AB - Due to its disruptive effects on circadian rhythms and sleep deprivation at night, shiftworking is currently recognized as a risk factor for breast cancer (BC). As revealed by the present analysis based on a comparative case-control study of 1679 women, exposure to light-at-night (LAN) in the "sleeping habitat" is significantly associated with BC risk (odds ratio [OR]=1.220, 95% confidence interval [CI]=1.118-1.311; p<.001), controlling for education, ethnicity, fertility, and alcohol consumption. The novelty of the present research is that, to the best of the authors' knowledge, it is the first study to have identified an unequivocal positive association between bedroom-light intensity and BC risk. Thus, according to the results of the present study, not only should artificial light exposure in the working environment be considered as a potential risk factor for BC, but also LAN in the "sleeping habitat."
UR - http://www.scopus.com/inward/record.url?scp=79955164160&partnerID=8YFLogxK
U2 - 10.3109/07420528.2010.531490
DO - 10.3109/07420528.2010.531490
M3 - Article
C2 - 21182407
AN - SCOPUS:79955164160
SN - 0743-9539
VL - 28
SP - 76
EP - 80
JO - Chronobiology International
JF - Chronobiology International
IS - 1
ER -