TY - JOUR
T1 - Divergence of Drosophila melanogaster repeatomes in response to a sharp microclimate contrast in Evolution Canyon, Israel
AU - Kim, Young Bun
AU - Oh, Jung Hun
AU - McIver, Lauren J.
AU - Rashkovetsky, Eugenia
AU - Michalak, Katarzyna
AU - Garner, Harold R.
AU - Kang, Lin
AU - Nevo, Eviatar
AU - Korol, Abraham B.
AU - Michalak, Pawel
PY - 2014/7/22
Y1 - 2014/7/22
N2 - Repeat sequences, especially mobile elements, make up large portions of most eukaryotic genomes and provide enormous, albeit commonly underappreciated, evolutionary potential. We analyzed repeatomes of Drosophila melanogaster that have been diverging in response to a microclimate contrast in Evolution Canyon (Mount Carmel, Israel), a natural evolutionary laboratory with two abutting slopes at an average distance of only 200 m, which pose a constant ecological challenge to their local biotas. Flies inhabiting the colder and more humid north-facing slope carried about 6% more transposable elements than those from the hot and dry south-facing slope, in parallel to a suite of other genetic and phenotypic differences between the two populations. Nearly 50% of all mobile element insertions were slope unique, with many of them disrupting coding sequences of genes critical for cognition, olfaction, and thermotolerance, consistent with the observed patterns of thermotolerance differences and assortative mating.
AB - Repeat sequences, especially mobile elements, make up large portions of most eukaryotic genomes and provide enormous, albeit commonly underappreciated, evolutionary potential. We analyzed repeatomes of Drosophila melanogaster that have been diverging in response to a microclimate contrast in Evolution Canyon (Mount Carmel, Israel), a natural evolutionary laboratory with two abutting slopes at an average distance of only 200 m, which pose a constant ecological challenge to their local biotas. Flies inhabiting the colder and more humid north-facing slope carried about 6% more transposable elements than those from the hot and dry south-facing slope, in parallel to a suite of other genetic and phenotypic differences between the two populations. Nearly 50% of all mobile element insertions were slope unique, with many of them disrupting coding sequences of genes critical for cognition, olfaction, and thermotolerance, consistent with the observed patterns of thermotolerance differences and assortative mating.
KW - Adaptive evolution
KW - Genome sequencing
KW - Incipient speciation
KW - Microsatellite
UR - http://www.scopus.com/inward/record.url?scp=84904604550&partnerID=8YFLogxK
U2 - 10.1073/pnas.1410372111
DO - 10.1073/pnas.1410372111
M3 - Article
C2 - 25006263
AN - SCOPUS:84904604550
SN - 0027-8424
VL - 111
SP - 10630
EP - 10635
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 29
ER -