Dioxin-like biological activity of organic extracts from sediments and fish livers sampled along the Israeli Mediterranean and Red Sea coasts

Yana Yudkovski; Barak Herut; Edna Shefer; Moshe Tom

doi:10.1016/j.marpolbul.2015.06.045

Dioxin-like biological activity of organic extracts from sediments and fish livers sampled along the Israeli Mediterranean and Red Sea coasts

Yana Yudkovski, Barak Herut, Edna Shefer, Moshe Tom

Research output: Contribution to journal › Article › peer-review

Abstract

This study provides, for the first time, a baseline evaluation of dioxin-like biological activity in sediments and fish sampled in- and adjacent to anchorages along the Mediterranean and Red Sea coasts of Israel. It indicates the effect of past pollution, still present in the sediments of older Israeli harbors, with putative contribution of still existing sources of pollution. A commercial reporter gene bioassay was used to evaluate the biological activity of dioxin-like compounds extracted from the samples. HRGC/HRMS analysis of several samples contributed a profile of dioxin-like compounds in sediments and fish. The results point out 1,2,3,4,6,7,8-HeptaCDD, 2,3,4,6,7,8-HexaCDF, 1,2,3,4,6,7,8-HeptaCDF, R{cyrillic}s{cyrillic}V{cyrillic}-126 and R{cyrillic}s{cyrillic}V{cyrillic}-118 as major contributors to the dioxin-like activity in sediments. It indicates polychlorinated biphenyls non-selective absorption in fish livers, in contrary to a biased accumulation of poorly chlorinated and more potent dibenzodioxins and dibenzofurans.

Original language	English
Pages (from-to)	295-300
Number of pages	6
Journal	Marine Pollution Bulletin
Volume	98
Issue number	1-2
DOIs	https://doi.org/10.1016/j.marpolbul.2015.06.045
State	Published - 15 Sep 2015
Externally published	Yes

Bibliographical note

Funding Information:
The study was supported by the European Union PF7 program grant, Perseus (287600) to M.T. and B.H., Israel Ministry of infrastructure grant (29-17-054) to M.T. and B.H., Israel Ministry of Environmental Protection, grant (103-12-4) to M.T. and Y.Y. Dr. Peter Behnisch and Mr. Emiel Felzel from BioDtection Systems, Amsterdam, are thanked for their kind advices and assistance during the performance of the biological and GCMS evaluations. The assistance of Dr. Maya Marmori from the Chemistry department of the Israel Oceanographic and Limnological Research in operating the MARSexpress device and in providing fish samples is appreciated. And last, the English editing of Ms. Lilach Baumer is thanked.

Publisher Copyright:
© 2015 Elsevier Ltd.

Keywords

DR-CALUX reporter gene assay
Dioxin-like activity
Israel coastal environment
Polychlorinated biphenyls
Polychlorinated dibenzodioxins/dibenzofurans

ASJC Scopus subject areas

Oceanography
Aquatic Science
Pollution

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10.1016/j.marpolbul.2015.06.045

Cite this

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title = "Dioxin-like biological activity of organic extracts from sediments and fish livers sampled along the Israeli Mediterranean and Red Sea coasts",

abstract = "This study provides, for the first time, a baseline evaluation of dioxin-like biological activity in sediments and fish sampled in- and adjacent to anchorages along the Mediterranean and Red Sea coasts of Israel. It indicates the effect of past pollution, still present in the sediments of older Israeli harbors, with putative contribution of still existing sources of pollution. A commercial reporter gene bioassay was used to evaluate the biological activity of dioxin-like compounds extracted from the samples. HRGC/HRMS analysis of several samples contributed a profile of dioxin-like compounds in sediments and fish. The results point out 1,2,3,4,6,7,8-HeptaCDD, 2,3,4,6,7,8-HexaCDF, 1,2,3,4,6,7,8-HeptaCDF, R{cyrillic}s{cyrillic}V{cyrillic}-126 and R{cyrillic}s{cyrillic}V{cyrillic}-118 as major contributors to the dioxin-like activity in sediments. It indicates polychlorinated biphenyls non-selective absorption in fish livers, in contrary to a biased accumulation of poorly chlorinated and more potent dibenzodioxins and dibenzofurans.",

keywords = "DR-CALUX reporter gene assay, Dioxin-like activity, Israel coastal environment, Polychlorinated biphenyls, Polychlorinated dibenzodioxins/dibenzofurans",

author = "Yana Yudkovski and Barak Herut and Edna Shefer and Moshe Tom",

note = "Funding Information: The study was supported by the European Union PF7 program grant, Perseus (287600) to M.T. and B.H., Israel Ministry of infrastructure grant (29-17-054) to M.T. and B.H., Israel Ministry of Environmental Protection, grant (103-12-4) to M.T. and Y.Y. Dr. Peter Behnisch and Mr. Emiel Felzel from BioDtection Systems, Amsterdam, are thanked for their kind advices and assistance during the performance of the biological and GCMS evaluations. The assistance of Dr. Maya Marmori from the Chemistry department of the Israel Oceanographic and Limnological Research in operating the MARSexpress device and in providing fish samples is appreciated. And last, the English editing of Ms. Lilach Baumer is thanked. Publisher Copyright: {\textcopyright} 2015 Elsevier Ltd.",

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doi = "10.1016/j.marpolbul.2015.06.045",

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AU - Herut, Barak

AU - Shefer, Edna

AU - Tom, Moshe

N1 - Funding Information: The study was supported by the European Union PF7 program grant, Perseus (287600) to M.T. and B.H., Israel Ministry of infrastructure grant (29-17-054) to M.T. and B.H., Israel Ministry of Environmental Protection, grant (103-12-4) to M.T. and Y.Y. Dr. Peter Behnisch and Mr. Emiel Felzel from BioDtection Systems, Amsterdam, are thanked for their kind advices and assistance during the performance of the biological and GCMS evaluations. The assistance of Dr. Maya Marmori from the Chemistry department of the Israel Oceanographic and Limnological Research in operating the MARSexpress device and in providing fish samples is appreciated. And last, the English editing of Ms. Lilach Baumer is thanked. Publisher Copyright: © 2015 Elsevier Ltd.

PY - 2015/9/15

Y1 - 2015/9/15

N2 - This study provides, for the first time, a baseline evaluation of dioxin-like biological activity in sediments and fish sampled in- and adjacent to anchorages along the Mediterranean and Red Sea coasts of Israel. It indicates the effect of past pollution, still present in the sediments of older Israeli harbors, with putative contribution of still existing sources of pollution. A commercial reporter gene bioassay was used to evaluate the biological activity of dioxin-like compounds extracted from the samples. HRGC/HRMS analysis of several samples contributed a profile of dioxin-like compounds in sediments and fish. The results point out 1,2,3,4,6,7,8-HeptaCDD, 2,3,4,6,7,8-HexaCDF, 1,2,3,4,6,7,8-HeptaCDF, R{cyrillic}s{cyrillic}V{cyrillic}-126 and R{cyrillic}s{cyrillic}V{cyrillic}-118 as major contributors to the dioxin-like activity in sediments. It indicates polychlorinated biphenyls non-selective absorption in fish livers, in contrary to a biased accumulation of poorly chlorinated and more potent dibenzodioxins and dibenzofurans.

AB - This study provides, for the first time, a baseline evaluation of dioxin-like biological activity in sediments and fish sampled in- and adjacent to anchorages along the Mediterranean and Red Sea coasts of Israel. It indicates the effect of past pollution, still present in the sediments of older Israeli harbors, with putative contribution of still existing sources of pollution. A commercial reporter gene bioassay was used to evaluate the biological activity of dioxin-like compounds extracted from the samples. HRGC/HRMS analysis of several samples contributed a profile of dioxin-like compounds in sediments and fish. The results point out 1,2,3,4,6,7,8-HeptaCDD, 2,3,4,6,7,8-HexaCDF, 1,2,3,4,6,7,8-HeptaCDF, R{cyrillic}s{cyrillic}V{cyrillic}-126 and R{cyrillic}s{cyrillic}V{cyrillic}-118 as major contributors to the dioxin-like activity in sediments. It indicates polychlorinated biphenyls non-selective absorption in fish livers, in contrary to a biased accumulation of poorly chlorinated and more potent dibenzodioxins and dibenzofurans.

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KW - Israel coastal environment

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SN - 0025-326X

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EP - 300

JO - Marine Pollution Bulletin

JF - Marine Pollution Bulletin

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ER -

Dioxin-like biological activity of organic extracts from sediments and fish livers sampled along the Israeli Mediterranean and Red Sea coasts

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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