לציטין סויה מעכב את תפקוד הטסיות ומפחית את רמות השומנים בדם

Translated title of the contribution: Soya lecithin inhibits platelet function and reduces blood lipid levels

M. Aviram, S. Linn, G. J. Brook

Research output: Contribution to journalArticlepeer-review

Abstract

Elevated plasma lipid concentrations and increased platelet activation are important risk factors in the development of atherosclerosis. 17 hypertriglyceridemic patients received increasing dosages of soya lecithin for 1-month periods (6, 12 and 18 g/day) with 1-month washout periods, during which no lecithin was given, before and between the treatment months. Plasma triglycerides were reduced by 35% and plasma cholesterol was 18%. ApoA-1 increased by 20% but no significant changes were noted in ApoB concentration. Both LDL and VLDL cholesterol levels were reduced and HDL cholesterol concentration increased. Platelet aggregation in response to collagen and ADP was significantly reduced, paralleling the reduction in triglyceride levels. The optimal effect was achieved with a daily dose of 12 g of lecithin. Supplementing the diet with soya lecithin may be useful in the management of the hypertriglyceridemic patient.

Translated title of the contributionSoya lecithin inhibits platelet function and reduces blood lipid levels
Original languageHebrew
Pages (from-to)122-123
Journalהרפואה
Volume107
Issue number5-6
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine

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