Diet quality in relation to healthy ageing: The Israeli Longitudinal Study on Aging (ILSA) - A study protocol

Abigail Goshen; Uri Goldbourt; Tamar Shohat; Tal Shimony; Lital Keinan-Boker; Yariv Gerber

doi:10.1136/bmjopen-2018-024673

Diet quality in relation to healthy ageing: The Israeli Longitudinal Study on Aging (ILSA) - A study protocol

Abigail Goshen, Uri Goldbourt, Tamar Shohat, Tal Shimony, Lital Keinan-Boker, Yariv Gerber

Research output: Contribution to journal › Article › peer-review

Abstract

Introduction Population ageing is accelerating rapidly in Israel as well as worldwide, necessitating adaptation of the healthcare system and consideration of new approaches that serve the specific needs of older adults. In addition to cognitive function, frailty is one of the most challenging expressions of physical and mental ageing, a multidimensional syndrome of increased vulnerability. Several studies have shown that low intake of certain micronutrients and protein is associated with higher risk of frailty and cognitive impairment. However, whether global diet quality is involved in the aetiology of the latter outcomes is unclear. Methods and analysis We are conducting, among older adult subjects who took part in 'Mabat Zahav' (Israeli National Health and Nutrition Survey of Older Adults) in 2005-2006 (T0, n=1852), an extensive follow-up interview (T1) that includes comprehensive geriatric assessment and evaluation of general health and quality of life. Diet quality is evaluated using the Healthy Eating Index (HEI) 2010, based on 24-hour diet recall measured at T0 and T1. Frailty is assessed using two different approaches: the phenotype framework and the accumulation of deficits model. Cognitive function is assessed by Mini-Mental State Examination (MMSE) and cognitive decline is assessed by the difference between repeated MMSE measurements. Different analytic methods will be applied to evaluate the role of diet quality in development of frailty and cognitive decline with inverse probability weighting used to minimise attrition bias. About 600 subjects are expected to be interviewed between May 2017 and December 2019. Ethics and dissemination Ethical approval was obtained from the Helsinki Committee of Sheba Medical Center, Tel Hashomer, Israel and the Ethical Committee of Tel-Aviv University. All participants sign an informed consent form. The findings of the study will be published in peer-reviewed journals.

Original language	English
Article number	e024673
Journal	BMJ Open
Volume	9
Issue number	4
DOIs	https://doi.org/10.1136/bmjopen-2018-024673
State	Published - 1 Apr 2019
Externally published	Yes

Bibliographical note

Funding Information:
Funding This study is supported by grant no .3-12787 from the Chief Scientist Office, Ministry of Health (principal investigator: YG) and The Bircher-Benner Foundation, Tel Aviv University (principal investigator: YG).

Funding Information:
We are indebted to all those who agree to participate in the study for their cooperation and patience answering our comprehensive questionnaire and their willingness to let us into their homes. We are grateful for our professional and dedicated study team: Osnat Fried, BSc; Michal Weber, BSc, RD; Rana Younis, BSc, RD and Polina Pokrass, BA, RN. This work was performed in partial fulfilment of the requirements for a PhD degree of Abigail Goshen, Sackler Faculty of Medicine, Tel Aviv University, Israel. This study is supported by grant no .3-12787 from the Chief Scientist Office, Ministry of Health (principal investigator: YG) and The Bircher-Benner Foundation, Tel Aviv University (principal investigator: YG).

Publisher Copyright:
© 2019 Author(s).

Keywords

diet quality
epidemiology
healthy aging
longitudinal studies
older adults

ASJC Scopus subject areas

Medicine (all)

Access to Document

10.1136/bmjopen-2018-024673

Cite this

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title = "Diet quality in relation to healthy ageing: The Israeli Longitudinal Study on Aging (ILSA) - A study protocol",

abstract = "Introduction Population ageing is accelerating rapidly in Israel as well as worldwide, necessitating adaptation of the healthcare system and consideration of new approaches that serve the specific needs of older adults. In addition to cognitive function, frailty is one of the most challenging expressions of physical and mental ageing, a multidimensional syndrome of increased vulnerability. Several studies have shown that low intake of certain micronutrients and protein is associated with higher risk of frailty and cognitive impairment. However, whether global diet quality is involved in the aetiology of the latter outcomes is unclear. Methods and analysis We are conducting, among older adult subjects who took part in 'Mabat Zahav' (Israeli National Health and Nutrition Survey of Older Adults) in 2005-2006 (T0, n=1852), an extensive follow-up interview (T1) that includes comprehensive geriatric assessment and evaluation of general health and quality of life. Diet quality is evaluated using the Healthy Eating Index (HEI) 2010, based on 24-hour diet recall measured at T0 and T1. Frailty is assessed using two different approaches: the phenotype framework and the accumulation of deficits model. Cognitive function is assessed by Mini-Mental State Examination (MMSE) and cognitive decline is assessed by the difference between repeated MMSE measurements. Different analytic methods will be applied to evaluate the role of diet quality in development of frailty and cognitive decline with inverse probability weighting used to minimise attrition bias. About 600 subjects are expected to be interviewed between May 2017 and December 2019. Ethics and dissemination Ethical approval was obtained from the Helsinki Committee of Sheba Medical Center, Tel Hashomer, Israel and the Ethical Committee of Tel-Aviv University. All participants sign an informed consent form. The findings of the study will be published in peer-reviewed journals.",

keywords = "diet quality, epidemiology, healthy aging, longitudinal studies, older adults",

author = "Abigail Goshen and Uri Goldbourt and Tamar Shohat and Tal Shimony and Lital Keinan-Boker and Yariv Gerber",

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AU - Shohat, Tamar

AU - Shimony, Tal

AU - Keinan-Boker, Lital

AU - Gerber, Yariv

N1 - Funding Information: Funding This study is supported by grant no .3-12787 from the Chief Scientist Office, Ministry of Health (principal investigator: YG) and The Bircher-Benner Foundation, Tel Aviv University (principal investigator: YG). Funding Information: We are indebted to all those who agree to participate in the study for their cooperation and patience answering our comprehensive questionnaire and their willingness to let us into their homes. We are grateful for our professional and dedicated study team: Osnat Fried, BSc; Michal Weber, BSc, RD; Rana Younis, BSc, RD and Polina Pokrass, BA, RN. This work was performed in partial fulfilment of the requirements for a PhD degree of Abigail Goshen, Sackler Faculty of Medicine, Tel Aviv University, Israel. This study is supported by grant no .3-12787 from the Chief Scientist Office, Ministry of Health (principal investigator: YG) and The Bircher-Benner Foundation, Tel Aviv University (principal investigator: YG). Publisher Copyright: © 2019 Author(s).

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N2 - Introduction Population ageing is accelerating rapidly in Israel as well as worldwide, necessitating adaptation of the healthcare system and consideration of new approaches that serve the specific needs of older adults. In addition to cognitive function, frailty is one of the most challenging expressions of physical and mental ageing, a multidimensional syndrome of increased vulnerability. Several studies have shown that low intake of certain micronutrients and protein is associated with higher risk of frailty and cognitive impairment. However, whether global diet quality is involved in the aetiology of the latter outcomes is unclear. Methods and analysis We are conducting, among older adult subjects who took part in 'Mabat Zahav' (Israeli National Health and Nutrition Survey of Older Adults) in 2005-2006 (T0, n=1852), an extensive follow-up interview (T1) that includes comprehensive geriatric assessment and evaluation of general health and quality of life. Diet quality is evaluated using the Healthy Eating Index (HEI) 2010, based on 24-hour diet recall measured at T0 and T1. Frailty is assessed using two different approaches: the phenotype framework and the accumulation of deficits model. Cognitive function is assessed by Mini-Mental State Examination (MMSE) and cognitive decline is assessed by the difference between repeated MMSE measurements. Different analytic methods will be applied to evaluate the role of diet quality in development of frailty and cognitive decline with inverse probability weighting used to minimise attrition bias. About 600 subjects are expected to be interviewed between May 2017 and December 2019. Ethics and dissemination Ethical approval was obtained from the Helsinki Committee of Sheba Medical Center, Tel Hashomer, Israel and the Ethical Committee of Tel-Aviv University. All participants sign an informed consent form. The findings of the study will be published in peer-reviewed journals.

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Diet quality in relation to healthy ageing: The Israeli Longitudinal Study on Aging (ILSA) - A study protocol

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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