TY - JOUR
T1 - Development and validation of the mobility in middle-age questionnaire
AU - Hayek, Roee
AU - Karvonen-Gutierrez, Carrie A.
AU - Bean, Jonathan F.
AU - Guralnik, Jack M.
AU - Covinsky, Kenneth
AU - Hoffman, Jay R.
AU - Azmon, Michal
AU - Yogev-Seligmann, Galit
AU - Krautner, Gregory
AU - Saad, Odelyah
AU - Nudelman, Yaniv
AU - Brown, Rebecca T.
AU - Springer, Shmuel
N1 - Publisher Copyright:
© The Author(s) 2025. Published by Oxford University Press on behalf of the Gerontological Society of America.
PY - 2025/12/1
Y1 - 2025/12/1
N2 - Background: Mobility decline often begins in midlife, and early identification of individuals at risk of accelerated deterioration can enable timely prevention. However, there is no validated self-report instrument that specifically assesses mobility in the middle-aged population. Methods: The Mobility in Middle-Age Questionnaire (MMQ) was developed through a 7-step Delphi process, consisting of 10 experts, involving item selection and content validation in both English and Hebrew, comprising 2 factors: (1) Current Mobility Ability and (2) 1-Year Mobility Change. Psychometric properties were assessed in 610 US and 594 Israeli middle-aged adults. Analyses included internal consistency, test–retest reliability, structural and construct validity (using the 10-item Physical Functioning scale [PF-10] from SF-36), and floor/ceiling effect assessments. A “Potential Mobility Risk Zone” was defined as the lowest 20% of MMQ scores. Results: The MMQ showed excellent internal consistency (Cronbach’s α=.94 English; .92 Hebrew) and strong test–retest reliability (intraclass correlation coefficient=0.89-0.90). Exploratory factor analysis explained 66% of variance; confirmatory factor analysis showed good fit (Comparative Fit Index=0.99, Tucker–Lewis Index=0.99, Standardized Root Mean Square Residual=0.05). Construct validity was supported, with all pre-defined hypotheses confirmed. MMQ showed significantly lower ceiling effects than PF-10 (3.9% vs. 34.5% in United States; 0.17% vs 25.25% in Israel, p < .001, large effect sizes). A score of 50 (20th percentile) was proposed as a preliminary “Potential Mobility Risk” Threshold. Conclusions: The MMQ is a reliable and valid tool for detecting early mobility decline in midlife. Longitudinal studies are needed to confirm its predictive value and responsiveness to change.
AB - Background: Mobility decline often begins in midlife, and early identification of individuals at risk of accelerated deterioration can enable timely prevention. However, there is no validated self-report instrument that specifically assesses mobility in the middle-aged population. Methods: The Mobility in Middle-Age Questionnaire (MMQ) was developed through a 7-step Delphi process, consisting of 10 experts, involving item selection and content validation in both English and Hebrew, comprising 2 factors: (1) Current Mobility Ability and (2) 1-Year Mobility Change. Psychometric properties were assessed in 610 US and 594 Israeli middle-aged adults. Analyses included internal consistency, test–retest reliability, structural and construct validity (using the 10-item Physical Functioning scale [PF-10] from SF-36), and floor/ceiling effect assessments. A “Potential Mobility Risk Zone” was defined as the lowest 20% of MMQ scores. Results: The MMQ showed excellent internal consistency (Cronbach’s α=.94 English; .92 Hebrew) and strong test–retest reliability (intraclass correlation coefficient=0.89-0.90). Exploratory factor analysis explained 66% of variance; confirmatory factor analysis showed good fit (Comparative Fit Index=0.99, Tucker–Lewis Index=0.99, Standardized Root Mean Square Residual=0.05). Construct validity was supported, with all pre-defined hypotheses confirmed. MMQ showed significantly lower ceiling effects than PF-10 (3.9% vs. 34.5% in United States; 0.17% vs 25.25% in Israel, p < .001, large effect sizes). A score of 50 (20th percentile) was proposed as a preliminary “Potential Mobility Risk” Threshold. Conclusions: The MMQ is a reliable and valid tool for detecting early mobility decline in midlife. Longitudinal studies are needed to confirm its predictive value and responsiveness to change.
KW - Aging
KW - Delphi
KW - Early-detection
KW - Mid-life
KW - Self-reported
UR - https://www.scopus.com/pages/publications/105021284653
U2 - 10.1093/gerona/glaf205
DO - 10.1093/gerona/glaf205
M3 - Article
C2 - 41017642
AN - SCOPUS:105021284653
SN - 1079-5006
VL - 80
JO - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
JF - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
IS - 12
M1 - glaf205
ER -