Detection of quorum-sensing N-acyl homoserine lactone signal molecules by bacterial biosensors

Laura Steindler, Vittorio Venturi

Research output: Contribution to journalShort surveypeer-review

Abstract

Many Gram-negative bacteria use N-acyl homoserine lactones (AHLs) as quorum-sensing (QS) signal molecules. AHL QS has been the subject of extensive investigation in the last decade and has become a paradigm for bacterial intercellular signaling. Research in AHL QS has been considerably aided by simple methods devised to detect AHLs using bacterial biosensors that phenotypically respond when exposed to exogenous AHLs. This article reviews and discusses the currently available bacterial biosensors which can be used in detecting and studying the different AHLs.

Original languageEnglish
Pages (from-to)1-9
Number of pages9
JournalFEMS Microbiology Letters
Volume266
Issue number1
DOIs
StatePublished - Jan 2007
Externally publishedYes

Keywords

  • Bacterial communication
  • N-acyl homoserine lactone
  • Quorum sensing
  • Signal molecules

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology
  • Microbiology

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