Cytological diagnosis of primary leiomyosarcoma of bone: Case report

Isaac Cohen; Norman Loberant; Moshe Goldfeld; Gershon Volpin

doi:10.1002/dc.2046

Cytological diagnosis of primary leiomyosarcoma of bone: Case report

Isaac Cohen, Norman Loberant, Moshe Goldfeld, Gershon Volpin

Research output: Contribution to journal › Article › peer-review

Abstract

We report on a case of primary leiomyosarcoma of the bone in a 77-yr-old man. The patient presented with a painful, enlarging mass in the left shoulder of 6 mo duration. Radiography and computed tomography (CT) revealed a large destructive intramedullary lesion of the proximal humerus, with massive extension into the surrounding soft tissues. CT-guided fine-needle aspiration biopsies (FNAB) of both the bony and soft-tissue lesions were performed. Cytological examination showed a neoplastic process composed of spindle cells mixed with pleomorphic cells. The smooth muscle origin of the neoplastic cells was confirmed by immunocytochemical analysis. We describe the cytological features of this rare primary tumor of bone, and consider the differential diagnosis of spindle-cell neoplasms. Diagn. Cytophatol.

Original language	English
Pages (from-to)	239-243
Number of pages	5
Journal	Diagnostic Cytopathology
Volume	25
Issue number	4
DOIs	https://doi.org/10.1002/dc.2046
State	Published - 2001
Externally published	Yes

Keywords

Bone tumor
Cytological diagnosis
Leiomyosarcoma

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/dc.2046

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title = "Cytological diagnosis of primary leiomyosarcoma of bone: Case report",

abstract = "We report on a case of primary leiomyosarcoma of the bone in a 77-yr-old man. The patient presented with a painful, enlarging mass in the left shoulder of 6 mo duration. Radiography and computed tomography (CT) revealed a large destructive intramedullary lesion of the proximal humerus, with massive extension into the surrounding soft tissues. CT-guided fine-needle aspiration biopsies (FNAB) of both the bony and soft-tissue lesions were performed. Cytological examination showed a neoplastic process composed of spindle cells mixed with pleomorphic cells. The smooth muscle origin of the neoplastic cells was confirmed by immunocytochemical analysis. We describe the cytological features of this rare primary tumor of bone, and consider the differential diagnosis of spindle-cell neoplasms. Diagn. Cytophatol.",

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T2 - Case report

AU - Cohen, Isaac

AU - Loberant, Norman

AU - Goldfeld, Moshe

AU - Volpin, Gershon

PY - 2001

Y1 - 2001

N2 - We report on a case of primary leiomyosarcoma of the bone in a 77-yr-old man. The patient presented with a painful, enlarging mass in the left shoulder of 6 mo duration. Radiography and computed tomography (CT) revealed a large destructive intramedullary lesion of the proximal humerus, with massive extension into the surrounding soft tissues. CT-guided fine-needle aspiration biopsies (FNAB) of both the bony and soft-tissue lesions were performed. Cytological examination showed a neoplastic process composed of spindle cells mixed with pleomorphic cells. The smooth muscle origin of the neoplastic cells was confirmed by immunocytochemical analysis. We describe the cytological features of this rare primary tumor of bone, and consider the differential diagnosis of spindle-cell neoplasms. Diagn. Cytophatol.

AB - We report on a case of primary leiomyosarcoma of the bone in a 77-yr-old man. The patient presented with a painful, enlarging mass in the left shoulder of 6 mo duration. Radiography and computed tomography (CT) revealed a large destructive intramedullary lesion of the proximal humerus, with massive extension into the surrounding soft tissues. CT-guided fine-needle aspiration biopsies (FNAB) of both the bony and soft-tissue lesions were performed. Cytological examination showed a neoplastic process composed of spindle cells mixed with pleomorphic cells. The smooth muscle origin of the neoplastic cells was confirmed by immunocytochemical analysis. We describe the cytological features of this rare primary tumor of bone, and consider the differential diagnosis of spindle-cell neoplasms. Diagn. Cytophatol.

KW - Bone tumor

KW - Cytological diagnosis

KW - Leiomyosarcoma

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JO - Diagnostic Cytopathology

JF - Diagnostic Cytopathology

IS - 4

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Cytological diagnosis of primary leiomyosarcoma of bone: Case report

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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