CRISPR-Cas9 mediated d3GHR knockout in HEK293 cells: Revealing the longevity associated isoform stress resilience

Keyphrases

• Stress Resilience 100%
• Cas9 Protein 100%
• Growth Hormone Receptor 100%
• HEK293 Cells 100%
• Growth Hormone Receptor Gene 100%
• Signaling Pathway 66%
• Homozygote 66%
• Receptor Signaling 66%
• Growth Hormone 66%
• Heterozygote 66%
• UV Radiation 66%
• Signaling Cascades 33%
• Receptor-interacting Protein Kinase 1 (RIPK1) 33%
• Scientific Community 33%
• Aging Process 33%
• Physiological Response 33%
• Expression Level 33%
• Survival Rate 33%
• Metabolism 33%
• High Survival 33%
• Genetic Variation 33%
• Insulin-like Growth factor-1 33%
• Downstream Genes 33%
• Environmental Stressors 33%
• Exon 3 33%
• Biological Effects 33%
• Molecular Events 33%
• JAK-STAT 33%
• Illness Prevention 33%
• CRISPR Editing 33%
• Guide RNA (gRNA) 33%
• Fasting Condition 33%
• HEK293 Cell Line 33%

Biochemistry, Genetics and Molecular Biology

• Isoform 100%
• CRISPR/Cas9 100%
• Growth Hormone Receptor 100%
• Receptor Gene 50%
• Homozygote 33%
• Bovine Somatotropin 33%
• Growth Hormone 33%
• Lifespan 16%
• Genetic Divergence 16%
• Metabolic Pathway 16%
• Insulin-Like Growth Factor 1 16%
• Genetic Variation 16%
• Exon 16%
• Survival Rate 16%
• CRISPR 16%
• Growth, Development and Aging 16%
• Cas9 16%
• Guide RNA 16%
• Biological Activity 16%