Control of a community-wide outbreak of hepatitis A by mass vaccination with inactivated hepatitis A vaccine

C. Zamir, S. Rishpon, D. Zamir, A. Leventhal, N. Rimon, E. Ben-Porath

Research output: Contribution to journalArticlepeer-review

Abstract

The epidemiology and control of hepatitis A virus was investigated during an outbreak of hepatitis A in a village in Israel. Postexposure administration of immune globulin to contacts was ineffective in controlling the outbreak. However, within 2 weeks of starting a mass immunization campaign with hepatitis A vaccine, the incidence of hepatitis A declined dramatically; the last case occurred 6 weeks after the immunization program began. The study demonstrated that while postexposure administration of immune globulin may diminish but not entirely arrest transmission of hepatitis A virus, active hepatitis A vaccination is a safe and effective intervention that can be used safely in hepatitis A virus antibody-positive children.

Original languageEnglish
Pages (from-to)185-187
Number of pages3
JournalEuropean Journal of Clinical Microbiology and Infectious Diseases
Volume20
Issue number3
DOIs
StatePublished - 2001
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint

Dive into the research topics of 'Control of a community-wide outbreak of hepatitis A by mass vaccination with inactivated hepatitis A vaccine'. Together they form a unique fingerprint.

Cite this