Conditioned taste aversion and taste learning: Molecular mechanisms

In the last few years different researchers obtained valuable and important data on molecular and cellular mechanisms of taste and conditioned taste aversion learning. This chapter aims to introduce taste behavior in the context of laboratory attempts to uncover the biological mechanisms underlying taste learning and memory. Specifically, the chapter is focused neuroanatomically on the insular cortex, the amygdala, and the connection between the two using the long-term potentiation model. From a molecular perspective, the chapter discusses the neurotransmitters involved in taste learning, the role of the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway, and translation regulation. Finally, I suggest future research directions. It is not difficult to imagine that fast and exciting technological development in the life sciences will facilitate understanding of this highly complex subject.