Characteristics and outcomes of ptyalism gravidarum

Moshe Bronshtein, Ayala Gover, Ron Beloosesky, Hanin Dabaja, Yuval Ginsberg, Zeev Weiner, Nizar Khatib

Research output: Contribution to journalArticlepeer-review


Background: Ptyalism gravidarum (PG) is a condition of hypersalivation that affects pregnant women early in gestation. Symptoms include massive saliva volumes (up to 2 liters per day), swollen salivary glands, sleep deprivation, significant emotional distress, and social difficulties. Objectives: To examine maternal and fetal characteristics and pregnancy outcomes of patients with PG. Methods: Patients diagnosed with PG in our clinic during the years 2001–2016 were identified and contacted. Demographic data were extracted from patient charts and clinical and outcome data was collected via telephone interviews. Results: The incidence of PG was 1/963 (0.09%) in our sample. Eleven out of 22 women (40%) with PG were also diagnosed with hyperemesis gravidarum. Fetal gender did not increase the risk. Of the mothers presenting with PG, 37% had a positive family history for this condition. There was no associated increase in the rate of fetal or maternal complications. Two women reported a resolution of the symptoms immediately following hypnosis with acupuncture treatment. Conclusions: Although PG represents an unpleasant mental and physical condition, it does not pose any specific risk to the health of the mother or increase adverse perinatal outcomes for the fetus. Alternative medicine could play a role in the treatment of PG.

Original languageEnglish
Pages (from-to)573-575
Number of pages3
JournalIsrael Medical Association Journal
Issue number9
StatePublished - Sep 2018

Bibliographical note

Publisher Copyright:
© 2018, Israel Medical Association. All rights reserved.


  • Hyperemesis gravidarum (HG)
  • Hypersalivation
  • Pregnancy
  • Prenatal outcome
  • Ptyalism gravidarum (PG)

ASJC Scopus subject areas

  • General Medicine


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