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Central and opposing effects of IGF-I and IGF-binding protein-3 on systemic insulin action
Radhika H. Muzumdar
, Xiaohui Ma
, Sigal Fishman
, Xiaoman Yang
,
Gil Atzmon
, Patricia Vuguin
, Francine H. Einstein
, David Hwang
, Pinchas Cohen
, Nir Barzilai
Research output
:
Contribution to journal
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Article
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peer-review
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Keyphrases
Central Effects
100%
Central Nervous System
11%
Glucose Uptake
22%
Hepatic Glucose Production
11%
Hypothalamus
11%
IGF-binding protein-3
100%
Impaired Insulin Secretion
11%
Insulin
11%
Insulin Action
100%
Insulin Clamp
11%
Insulin Sensitizers
11%
Insulin-like Growth Factor 1 Receptor (IGF1R)
11%
Insulin-like Growth Factor Binding Protein (IGFBP)
11%
Insulin-like Growth factor-1
100%
Intracerebroventricular Injection
22%
Liver
33%
Metabolism
11%
Nuclear Localization Signal
11%
Opposing Effects
100%
Paucity
11%
Peripheral Insulin
11%
Physiological Effects
11%
Physiologically Relevant
11%
Protein System
11%
Biochemistry, Genetics and Molecular Biology
Binding Protein
100%
Gluconeogenesis
10%
Glucose Transport
20%
Insulin
100%
Insulin-Like Growth Factor 1 Receptor
10%
Metabolic Pathway
10%
Nuclear Localization Sequence
10%
Sensitization
10%