Cardiovascular responses to adrenergic agents in different acclimation states in the rock pigeon (columba livid)

E. Ophir; P. Raber; J. Marder; Y. Arieli

doi:10.1515/JBCPP.2002.13.1.1

Cardiovascular responses to adrenergic agents in different acclimation states in the rock pigeon (columba livid)

E. Ophir, P. Raber, J. Marder, Y. Arieli

Research output: Contribution to journal › Article › peer-review

Abstract

The effect of propranolol on heart rate (f_H) was measured in season-acclimatized pigeons. Propranolol treatment decreased f_H in winter-acclimatized pigeons, accelerated f_H in summer-acclimatized pigeons, but had no effect on f_H in spring-acclimatized pigeons. The effect of propranolol in summer-acclimatized pigeons is opposite to that observed in mammals. Interestingly, isoproterenol produced a propranolol-like cardioacceleration in heat-acclimated pigeons. We suggest that propranolol affects f_H in summer-acclimatized pigeons via two opposing routes—a direct and a peripheral indirect route. We also suggest that the cardiovascular effects of propranolol are involved in the capacity of the pigeon to evaporate water from its skin.

Original language	English
Pages (from-to)	1-10
Number of pages	10
Journal	Journal of Basic and Clinical Physiology and Pharmacology
Volume	13
Issue number	1
DOIs	https://doi.org/10.1515/JBCPP.2002.13.1.1
State	Published - 2002
Externally published	Yes

Keywords

cardioacceleration
isoproterenol
propranolol
thermoregulation

ASJC Scopus subject areas

Physiology
Pharmacology
Drug Discovery

Access to Document

10.1515/JBCPP.2002.13.1.1

Cite this

@article{5e6cce0e1d244431bf30865ea1fa3b74,

title = "Cardiovascular responses to adrenergic agents in different acclimation states in the rock pigeon (columba livid)",

abstract = "The effect of propranolol on heart rate (fH) was measured in season-acclimatized pigeons. Propranolol treatment decreased fH in winter-acclimatized pigeons, accelerated fH in summer-acclimatized pigeons, but had no effect on fH in spring-acclimatized pigeons. The effect of propranolol in summer-acclimatized pigeons is opposite to that observed in mammals. Interestingly, isoproterenol produced a propranolol-like cardioacceleration in heat-acclimated pigeons. We suggest that propranolol affects fH in summer-acclimatized pigeons via two opposing routes—a direct and a peripheral indirect route. We also suggest that the cardiovascular effects of propranolol are involved in the capacity of the pigeon to evaporate water from its skin.",

keywords = "cardioacceleration, isoproterenol, propranolol, thermoregulation",

author = "E. Ophir and P. Raber and J. Marder and Y. Arieli",

year = "2002",

doi = "10.1515/JBCPP.2002.13.1.1",

language = "English",

volume = "13",

pages = "1--10",

journal = "Journal of Basic and Clinical Physiology and Pharmacology",

issn = "0792-6855",

publisher = "Walter de Gruyter GmbH",

number = "1",

}

TY - JOUR

T1 - Cardiovascular responses to adrenergic agents in different acclimation states in the rock pigeon (columba livid)

AU - Ophir, E.

AU - Raber, P.

AU - Marder, J.

AU - Arieli, Y.

PY - 2002

Y1 - 2002

N2 - The effect of propranolol on heart rate (fH) was measured in season-acclimatized pigeons. Propranolol treatment decreased fH in winter-acclimatized pigeons, accelerated fH in summer-acclimatized pigeons, but had no effect on fH in spring-acclimatized pigeons. The effect of propranolol in summer-acclimatized pigeons is opposite to that observed in mammals. Interestingly, isoproterenol produced a propranolol-like cardioacceleration in heat-acclimated pigeons. We suggest that propranolol affects fH in summer-acclimatized pigeons via two opposing routes—a direct and a peripheral indirect route. We also suggest that the cardiovascular effects of propranolol are involved in the capacity of the pigeon to evaporate water from its skin.

AB - The effect of propranolol on heart rate (fH) was measured in season-acclimatized pigeons. Propranolol treatment decreased fH in winter-acclimatized pigeons, accelerated fH in summer-acclimatized pigeons, but had no effect on fH in spring-acclimatized pigeons. The effect of propranolol in summer-acclimatized pigeons is opposite to that observed in mammals. Interestingly, isoproterenol produced a propranolol-like cardioacceleration in heat-acclimated pigeons. We suggest that propranolol affects fH in summer-acclimatized pigeons via two opposing routes—a direct and a peripheral indirect route. We also suggest that the cardiovascular effects of propranolol are involved in the capacity of the pigeon to evaporate water from its skin.

KW - cardioacceleration

KW - isoproterenol

KW - propranolol

KW - thermoregulation

UR - http://www.scopus.com/inward/record.url?scp=0036403321&partnerID=8YFLogxK

U2 - 10.1515/JBCPP.2002.13.1.1

DO - 10.1515/JBCPP.2002.13.1.1

M3 - Article

C2 - 12099400

AN - SCOPUS:0036403321

SN - 0792-6855

VL - 13

SP - 1

EP - 10

JO - Journal of Basic and Clinical Physiology and Pharmacology

JF - Journal of Basic and Clinical Physiology and Pharmacology

IS - 1

ER -

Cardiovascular responses to adrenergic agents in different acclimation states in the rock pigeon (columba livid)

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this