Abstract
The treatment of neuropathic pain remains a challenge as it rarely leads to long-term relief of symptoms. We report three patients with chronic neuropathic pain, in whom acute administration of the N-methyl-D-aspartate (NMDA) receptor antagonist amantadine resulted in complete resolution of symptoms, presumably due to termination the central 'wind-up' phenomenon.
| Original language | English |
|---|---|
| Pages (from-to) | 337-339 |
| Number of pages | 3 |
| Journal | Pain |
| Volume | 74 |
| Issue number | 2-3 |
| DOIs | |
| State | Published - Jan 1998 |
Keywords
- 'wind-up' phenomenon
- Amantadine
- N-methyl-D-aspartate receptor
- Neuropathic pain
ASJC Scopus subject areas
- Neurology
- Clinical Neurology
- Anesthesiology and Pain Medicine