Calcium hunger in the parathyroidectomized rat is specific

Micah Leshem; Sonia Del Canho; Jay Schulkin

doi:10.1016/S0031-9384(99)00113-4

Calcium hunger in the parathyroidectomized rat is specific

Micah Leshem, Sonia Del Canho, Jay Schulkin

Department of Psychology

Research output: Contribution to journal › Article › peer-review

Abstract

Calcium ingestion consequent on a challenge to calcium homeostasis such as parathyroidectomy or calcium deficient diet often appears to be nonspecific: rats rendered calcium deficient by a calcium-deficient diet increase ingestion of many tastants besides calcium, including MgCl₂ and in particular, NaCl. Rats rendered calcium deficient by parathyroidectomy (PTX) have also been reported to increase ingestion of magnesium. Thus, magnesium, a chemically related molecule, and NaCl, a preferred mineral, pose challenges to the notion of a specific calcium hunger in calcium-deficient rats. Here, we reexamine the specificity of calcium preference of rats rendered calcium hungry by PTX by allowing them to choose between CaCl₂ and MgCl₂, and between CaCl₂ and NaCl. We find that PTX rats clearly prefer calcium to either tastant. A review of the literature on tastant selection by calcium-hungry rats suggests that, given the choice between calcium and other tastants, they prefer calcium. Our findings lend credence to the notion of a calcium specific appetite in calcium-deficient rats. Copyright (C) 1999 Elsevier Science Inc.

Original language	English
Pages (from-to)	555-559
Number of pages	5
Journal	Physiology and Behavior
Volume	67
Issue number	4
DOIs	https://doi.org/10.1016/S0031-9384(99)00113-4
State	Published - Oct 1999

Bibliographical note

Funding Information:
We thank Irit Akirav for valuable assistance. This work was supported by USA–Israel Binational Science Foundation (BSF) Grant No. 94-00206/1 to M.L. and J.S.

Keywords

Calcium deficiency
Ingestion
Mineral appetite
Parathyroid
Preference
Salt
Specific appetite
Taste

ASJC Scopus subject areas

Experimental and Cognitive Psychology
Behavioral Neuroscience

Access to Document

10.1016/S0031-9384(99)00113-4

Cite this

@article{b3ff5a76a311444aa2ccb25c8513bca9,

title = "Calcium hunger in the parathyroidectomized rat is specific",

abstract = "Calcium ingestion consequent on a challenge to calcium homeostasis such as parathyroidectomy or calcium deficient diet often appears to be nonspecific: rats rendered calcium deficient by a calcium-deficient diet increase ingestion of many tastants besides calcium, including MgCl2 and in particular, NaCl. Rats rendered calcium deficient by parathyroidectomy (PTX) have also been reported to increase ingestion of magnesium. Thus, magnesium, a chemically related molecule, and NaCl, a preferred mineral, pose challenges to the notion of a specific calcium hunger in calcium-deficient rats. Here, we reexamine the specificity of calcium preference of rats rendered calcium hungry by PTX by allowing them to choose between CaCl2 and MgCl2, and between CaCl2 and NaCl. We find that PTX rats clearly prefer calcium to either tastant. A review of the literature on tastant selection by calcium-hungry rats suggests that, given the choice between calcium and other tastants, they prefer calcium. Our findings lend credence to the notion of a calcium specific appetite in calcium-deficient rats. Copyright (C) 1999 Elsevier Science Inc.",

keywords = "Calcium deficiency, Ingestion, Mineral appetite, Parathyroid, Preference, Salt, Specific appetite, Taste",

author = "Micah Leshem and {Del Canho}, Sonia and Jay Schulkin",

note = "Funding Information: We thank Irit Akirav for valuable assistance. This work was supported by USA–Israel Binational Science Foundation (BSF) Grant No. 94-00206/1 to M.L. and J.S.",

year = "1999",

month = oct,

doi = "10.1016/S0031-9384(99)00113-4",

language = "English",

volume = "67",

pages = "555--559",

journal = "Physiology and Behavior",

issn = "0031-9384",

publisher = "Elsevier",

number = "4",

}

TY - JOUR

T1 - Calcium hunger in the parathyroidectomized rat is specific

AU - Leshem, Micah

AU - Del Canho, Sonia

AU - Schulkin, Jay

N1 - Funding Information: We thank Irit Akirav for valuable assistance. This work was supported by USA–Israel Binational Science Foundation (BSF) Grant No. 94-00206/1 to M.L. and J.S.

PY - 1999/10

Y1 - 1999/10

N2 - Calcium ingestion consequent on a challenge to calcium homeostasis such as parathyroidectomy or calcium deficient diet often appears to be nonspecific: rats rendered calcium deficient by a calcium-deficient diet increase ingestion of many tastants besides calcium, including MgCl2 and in particular, NaCl. Rats rendered calcium deficient by parathyroidectomy (PTX) have also been reported to increase ingestion of magnesium. Thus, magnesium, a chemically related molecule, and NaCl, a preferred mineral, pose challenges to the notion of a specific calcium hunger in calcium-deficient rats. Here, we reexamine the specificity of calcium preference of rats rendered calcium hungry by PTX by allowing them to choose between CaCl2 and MgCl2, and between CaCl2 and NaCl. We find that PTX rats clearly prefer calcium to either tastant. A review of the literature on tastant selection by calcium-hungry rats suggests that, given the choice between calcium and other tastants, they prefer calcium. Our findings lend credence to the notion of a calcium specific appetite in calcium-deficient rats. Copyright (C) 1999 Elsevier Science Inc.

AB - Calcium ingestion consequent on a challenge to calcium homeostasis such as parathyroidectomy or calcium deficient diet often appears to be nonspecific: rats rendered calcium deficient by a calcium-deficient diet increase ingestion of many tastants besides calcium, including MgCl2 and in particular, NaCl. Rats rendered calcium deficient by parathyroidectomy (PTX) have also been reported to increase ingestion of magnesium. Thus, magnesium, a chemically related molecule, and NaCl, a preferred mineral, pose challenges to the notion of a specific calcium hunger in calcium-deficient rats. Here, we reexamine the specificity of calcium preference of rats rendered calcium hungry by PTX by allowing them to choose between CaCl2 and MgCl2, and between CaCl2 and NaCl. We find that PTX rats clearly prefer calcium to either tastant. A review of the literature on tastant selection by calcium-hungry rats suggests that, given the choice between calcium and other tastants, they prefer calcium. Our findings lend credence to the notion of a calcium specific appetite in calcium-deficient rats. Copyright (C) 1999 Elsevier Science Inc.

KW - Calcium deficiency

KW - Ingestion

KW - Mineral appetite

KW - Parathyroid

KW - Preference

KW - Salt

KW - Specific appetite

KW - Taste

UR - http://www.scopus.com/inward/record.url?scp=0032832947&partnerID=8YFLogxK

U2 - 10.1016/S0031-9384(99)00113-4

DO - 10.1016/S0031-9384(99)00113-4

M3 - Article

C2 - 10549893

AN - SCOPUS:0032832947

SN - 0031-9384

VL - 67

SP - 555

EP - 559

JO - Physiology and Behavior

JF - Physiology and Behavior

IS - 4

ER -

Calcium hunger in the parathyroidectomized rat is specific

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this