Bullous herpes zoster in a child with leukemia: Case report and review of the literature

Motti Haimi, Myriam Weyl Ben-Arush, Imad Kassis, Sergey Postovsky, Zipi Kra-Oz, Ronit Elhasid

Research output: Contribution to journalReview articlepeer-review


Blistering disorders in childhood are usually difficult to diagnose and pose complicated management dilemmas. The incidence of herpes zoster in children with malignancy and immunodeficiency is greatly increased compared to normal children of comparable age. Although herpes zoster is known to occur in children with malignancy, the bullous form of herpes zoster is rare; to the authors' knowledge, there was no previous report of this phenomenon in children in general and in children with cancer in particular. The authors describe a 3.5-year-old girl who was diagnosed with acute lymphoblastic leukemia; 7 months after presentation, during chemotherapy treatment, she developed the bullous form of herpes zoster on her right hand. The authors describe the method of diagnosis and provide a review of the literature concerning this rare phenomenon. Recognizing this entity and differentiating it from other bullomatous conditions enable the application of appropriate treatment, without unnecessary delay.

Original languageEnglish
Pages (from-to)587-590
Number of pages4
JournalJournal of Pediatric Hematology/Oncology
Issue number9
StatePublished - Sep 2004
Externally publishedYes


  • Acute lymphoblastic leukemia
  • Bullous
  • Herpes-zoster

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Pediatrics, Perinatology, and Child Health


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