Brain activity during processing objects and pseudo-objects: Comparison between adult regular and dyslexic readers

Naama Mayseless, Zvia Breznitz

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: The role of visual processing deficits in dyslexia remains unclear and continues to stir controversy. Most studies to date have used alphabetic and or other language-dependent patterns. The current study compares how dyslexics and regular readers process non-alphabetic visual patterns. Methods: The stimuli were black and white drawings, 50 meaningful (concrete objects) and 50 meaningless (pseudo-objects with no linguistic name) presented visually on a computer screen. Measures included behavioral accuracy and reaction time, event-related potential (ERP), and low resolution electromagnetic tomography (LORETA). The subjects were 15 dyslexic and 15 aged-matched regular readers. Results: The dyslexics exhibited significantly longer reaction time and shorter latencies of P1 and P2 components to both objects and pseudo-objects compared to the regular readers. Data from the LORETA solution analysis indicated significantly different brain activity between the two groups: both exhibited higher left hemisphere activation when viewing objects compared to pseudo-objects; and dyslexics exhibited lower left hemisphere activation when viewing objects and higher right hemisphere activation when viewing pseudo-objects during the early stages of processing. Conclusions: The results support the notion that brain activation of dyslexic readers differs from that of the regular readers when processing non-alphabetic patterns, and that the differences appear from the early stage of processing. Significance: These results emphasize that differences in brain activity between dyslexic and regular readers can be seen even in a non-alphabetic task, and in early stages of processing.

Original languageEnglish
Pages (from-to)284-298
Number of pages15
JournalClinical Neurophysiology
Volume122
Issue number2
DOIs
StatePublished - Feb 2011

Bibliographical note

Funding Information:
Research for this study was supported by a grant awarded by the Edmond J. Safra Philanthropic Foundation. The founders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Keywords

  • Dyslexia
  • Early processing
  • Event-related potentials (ERP)
  • Object recognition

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Sensory Systems
  • Physiology (medical)

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