Bioinformatics analyses of the transcriptome reveal Ube3a-dependent effects on mitochondrial-related pathways

Keyphrases

• Transcriptome 100%
• UBE3A 100%
• Related Pathway 100%
• Bioinformatics Analysis 100%
• Angelman Syndrome 20%
• Oxidative Stress 20%
• Mitochondrial Dysfunction 20%
• Mouse Embryonic Fibroblasts 20%
• Genotype 10%
• Machine Learning Approach 10%
• Transcriptomic Data 10%
• Autism 10%
• Neurodevelopmental Disorders 10%
• Publicly Available 10%
• Overexpression 10%
• E3 Ubiquitin Ligase 10%
• MRNA-seq 10%
• UBE3A Gene 10%
• Mitochondrial Function 10%
• Bioinformatics Methods 10%
• Human Transcriptome 10%
• Mitochondrial Genes 10%
• Bioinformatics Tools 10%
• Gene Expression Profile 10%
• Stress Dysregulation 10%
• 15q Duplication Syndrome 10%
• 15q Duplication 10%
• Resting Baseline 10%
• Baseline State 10%

Neuroscience

• Transcriptome 100%
• Angelman Syndrome 66%
• Oxidative Stress 66%
• Fibroblast 66%
• Gene Expression 33%
• Ubiquitin Protein Ligase E3 33%
• Messenger RNA 33%
• Autism 33%