Autoregulation of heat-shock system in Drosophila Melanogaster. Analysis of heat-shock response in a temperature-sensitive cell-lethal mutant

Michael B. Evgen'ev; Olga L. Zatsepina; Helen Titarenko

doi:10.1016/0014-5793(85)80388-4

Autoregulation of heat-shock system in Drosophila Melanogaster. Analysis of heat-shock response in a temperature-sensitive cell-lethal mutant

Michael B. Evgen'ev, Olga L. Zatsepina, Helen Titarenko

Research output: Contribution to journal › Article › peer-review

Abstract

The cells of the cell-lethal mutant 1(1)ts403 are characterized by an extremely low level of synthesis of heat-shock proteins (hsp) after temperature elevation. The mutation affects not only the kinetics of hsp synthesis but also the electrophoretic pattern of hsp. Studies of puffing, RNA and protein synthesis in the mutant strongly suggest that hsp are involved in the regulation of their own synthesis at the level of puff induction, transcription and translation.

Original language	English
Pages (from-to)	286-290
Number of pages	5
Journal	FEBS Letters
Volume	188
Issue number	2
DOIs	https://doi.org/10.1016/0014-5793(85)80388-4
State	Published - 2 Sep 1985
Externally published	Yes

Keywords

Drosophila ts mutation
Heat-shock protein
Puffing

ASJC Scopus subject areas

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics
Cell Biology

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10.1016/0014-5793(85)80388-4

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abstract = "The cells of the cell-lethal mutant 1(1)ts403 are characterized by an extremely low level of synthesis of heat-shock proteins (hsp) after temperature elevation. The mutation affects not only the kinetics of hsp synthesis but also the electrophoretic pattern of hsp. Studies of puffing, RNA and protein synthesis in the mutant strongly suggest that hsp are involved in the regulation of their own synthesis at the level of puff induction, transcription and translation.",

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AU - Evgen'ev, Michael B.

AU - Zatsepina, Olga L.

AU - Titarenko, Helen

PY - 1985/9/2

Y1 - 1985/9/2

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AB - The cells of the cell-lethal mutant 1(1)ts403 are characterized by an extremely low level of synthesis of heat-shock proteins (hsp) after temperature elevation. The mutation affects not only the kinetics of hsp synthesis but also the electrophoretic pattern of hsp. Studies of puffing, RNA and protein synthesis in the mutant strongly suggest that hsp are involved in the regulation of their own synthesis at the level of puff induction, transcription and translation.

KW - Drosophila ts mutation

KW - Heat-shock protein

KW - Puffing

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ER -

Autoregulation of heat-shock system in Drosophila Melanogaster. Analysis of heat-shock response in a temperature-sensitive cell-lethal mutant

Abstract

Keywords

ASJC Scopus subject areas

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