TY - JOUR
T1 - Associations between exposure to industrial air pollution and prevalence of asthma and atopic diseases in haifa bay area
AU - Raz, Raanan
AU - Yuval,
AU - Bar-Or, Ruth Lev
AU - Kark, Jeremy D.
AU - Sinnreich, Ronit
AU - Broday, David M.
AU - Harari-Kremer, Ruthie
AU - Bentur, Lea
AU - Gileles-Hillel, Alex
AU - Keinan-Boker, Lital
AU - Lyubarsky, Andrey
AU - Tsur, Dorit
AU - Afek, Arnon
AU - Levin, Noam
AU - Derazne, Estela
AU - Twig, Gilad
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/4
Y1 - 2021/4
N2 - Haifa Bay Area (HBA) contains Israel’s principal industrial area, and there are substantial public concerns about health effects from its emissions. We aimed to examine associations between exposure to air pollution from HBA industrial area with prevalent asthma and other atopic diseases at age 17. This is a cross-sectional study. The study population included all adolescents born in Israel and whose medical status was evaluated for mandatory military recruitment by the Israeli medical corps during 1967-2017. We analyzed prevalent asthma, allergic rhinitis, atopic dermatitis, and rhinoconjunctivitis. We estimated exposure to industrial air pollution by a kriging interpolation of historical SO2 observations and adjusted the associations to the year of birth, SES, school orientation, and traffic pollution. The study population included n = 2, 523, 745 adolescents, among which 5.9% had prevalent asthma and 4.6%had allergic rhinitis. Residency inHBAwas associatedwith a higher adjusted risk of asthma, compared with non-HBA residency. Still, this association was limited to the three lowest exposure categories, while the highest exposure group had the lowest adjusted risk. Sensitivity analyses and other atopic diseases presented similar results. These results do not provide support for causal relationships between HBA industry-related emissions and prevalent atopic diseases.
AB - Haifa Bay Area (HBA) contains Israel’s principal industrial area, and there are substantial public concerns about health effects from its emissions. We aimed to examine associations between exposure to air pollution from HBA industrial area with prevalent asthma and other atopic diseases at age 17. This is a cross-sectional study. The study population included all adolescents born in Israel and whose medical status was evaluated for mandatory military recruitment by the Israeli medical corps during 1967-2017. We analyzed prevalent asthma, allergic rhinitis, atopic dermatitis, and rhinoconjunctivitis. We estimated exposure to industrial air pollution by a kriging interpolation of historical SO2 observations and adjusted the associations to the year of birth, SES, school orientation, and traffic pollution. The study population included n = 2, 523, 745 adolescents, among which 5.9% had prevalent asthma and 4.6%had allergic rhinitis. Residency inHBAwas associatedwith a higher adjusted risk of asthma, compared with non-HBA residency. Still, this association was limited to the three lowest exposure categories, while the highest exposure group had the lowest adjusted risk. Sensitivity analyses and other atopic diseases presented similar results. These results do not provide support for causal relationships between HBA industry-related emissions and prevalent atopic diseases.
KW - Asthma
KW - Atopic diseases
KW - Haifa bay area
KW - Industrial air pollution
UR - http://www.scopus.com/inward/record.url?scp=85106994398&partnerID=8YFLogxK
U2 - 10.3390/atmos12040516
DO - 10.3390/atmos12040516
M3 - Article
AN - SCOPUS:85106994398
SN - 2073-4433
VL - 12
JO - ATMOSPHERE
JF - ATMOSPHERE
IS - 4
M1 - 516
ER -
