Assessment of Endogenous Pain-Inhibition Processes Through the Conditioned Pain Modulation (CPM) and the Offset Analgesia Paradigms

Roi Treister; David Yarnitsky; Yelena Granovsky

doi:10.1016/B978-0-12-805408-6.00037-3

Assessment of Endogenous Pain-Inhibition Processes Through the Conditioned Pain Modulation (CPM) and the Offset Analgesia Paradigms

Roi Treister, David Yarnitsky, Yelena Granovsky

Department of Nursing

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Conditioned pain modulation (CPM) and offset analgesia (OA) are two psychophysical paradigms used for the assessment of endogenous pain modulation. Their mode of action is based on spatial and temporal filtering of nociceptive information, respectively, via activation of pain inhibitory mechanisms. Despite distinct brain mechanisms, both responses are deficient in patients with chronic pain. The CPM response had been proven for the prediction of pain acquisition and pain treatment success.

Original language	English
Title of host publication	The Senses
Subtitle of host publication	A Comprehensive Reference: Volume 1-7, Second Edition
Publisher	Elsevier
Pages	791-800
Number of pages	10
Volume	5
ISBN (Electronic)	9780128054093
ISBN (Print)	9780128054086
DOIs	https://doi.org/10.1016/B978-0-12-805408-6.00037-3
State	Published - 1 Jan 2020

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Inc. All rights reserved.

Keywords

Chronic pain
Clinical relevance
Conditioned pain modulation
Endogenous analgesia
Mechanisms
Methodology
Offset analgesia
Pain
Pain facilitation
Pain inhibition

ASJC Scopus subject areas

General Medicine
General Neuroscience

Access to Document

10.1016/B978-0-12-805408-6.00037-3

Cite this

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Assessment of Endogenous Pain-Inhibition Processes Through the Conditioned Pain Modulation (CPM) and the Offset Analgesia Paradigms. / Treister, Roi; Yarnitsky, David; Granovsky, Yelena.
The Senses: A Comprehensive Reference: Volume 1-7, Second Edition. Vol. 5 Elsevier, 2020. p. 791-800.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

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KW - Pain facilitation

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Assessment of Endogenous Pain-Inhibition Processes Through the Conditioned Pain Modulation (CPM) and the Offset Analgesia Paradigms

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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