Anxiety sensitivity and anxious responding to bodily sensations: A test among adolescents using a voluntary hyperventilation challenge

Ellen W. Leen-Feldner, Matthew T. Feldner, Amit Bernstein, Justin T. McCormick, Michael J. Zvolensky

Research output: Contribution to journalArticlepeer-review


This study examined the general factor and lower-order facets of the Childhood Anxiety Sensitivity Index (CASI; W. K. Silverman, W. Flesig, B. Rabian, & R. A. Peterson, 1991) in relation to anxious and fearful responding to a 3-min voluntary hyperventilation procedure. Participants were 151 psychologically healthy adolescents (66 females), as indexed by a screening using the Anxiety Disorders Interview Schedule for the Diagnostic and Statistical Manual-Fourth Edition (DSM-IV): Child Version (ADIS-C; W. K. Silverman & A. M. Albano, 1996), between the ages of 12 and 17 (M = 14.93). Results indicated, relative to negative affectivity and prechallenge ratings of anxiety, both the global factor and the Disease Concerns facet of the CASI significantly predicted postchallenge anxiety and intensity of panic symptoms. CASI total and subfactor scores were unrelated to psychophysiological responding to the challenge. Results are discussed in relation to panic-relevant emotional vulnerability among adolescents.

Original languageEnglish
Pages (from-to)593-609
Number of pages17
JournalCognitive Therapy and Research
Issue number5
StatePublished - Oct 2005
Externally publishedYes

Bibliographical note

Funding Information:
This project was supported by a grant from Child & Adolescent Research and Training, Inc. awarded to the first author, a National Research Service Award predoctoral fellowship (F31 MH66430-01) awarded to the second author, and National Institute on Drug Abuse research grants (R03 DA16307-01 and 1 R21 DA016227-01) and a Faculty Research Grant from the Anxiety Disorder Association of America awarded to the fifth author. The authors thank Stephanie Sinisi, Marc Hartigan, Lindsay Van Zanten, and Kate Follansbee for their assistance with this project.


  • Adolescents
  • Anxiety sensitivity
  • Hyperventilation challenge

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Clinical Psychology


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