Antioxidant effect of polyphenolic glabridin on LDL oxidation

E. Carmeli, Y. Fogelman

Research output: Contribution to journalArticlepeer-review

Abstract

This study was conducted to determine the effect of a natural polyphenolic isoflavone antioxidant (Glabridin) on low-density lipoprotein (LDL) oxidation. Determination of the extent of LDL oxidation was done by measuring the formation of Thiobarbituric acid reactive substances (TBARS). After oral administration of licorice-root ethanol extract to healthy subjects for 6 months, the subjects’ oxidative stress level as well as plasma LDL oxidation reduced by 20%. We concluded that dietary consumption of glabridin protects LDL from oxidation.

Original languageEnglish
Pages (from-to)321-324
Number of pages4
JournalToxicology and Industrial Health
Volume25
Issue number5
DOIs
StatePublished - May 2009
Externally publishedYes

Keywords

  • LDL oxidation
  • Sienna conference
  • antiatherosclerotic affects
  • cardiovascular diseases
  • glabridin
  • licorice plant

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis
  • Toxicology

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