TY - JOUR
T1 - Ancient goat genomes reveal mosaic domestication in the Fertile Crescent
AU - Daly, Kevin G.
AU - Delser, Pierpaolo Maisano
AU - Mullin, Victoria E.
AU - Scheu, Amelie
AU - Mattiangeli, Valeria
AU - Teasdale, Matthew D.
AU - Hare, Andrew J.
AU - Burger, Joachim
AU - Verdugo, Marta Pereira
AU - Collins, Matthew J.
AU - Kehati, Ron
AU - Erek, Cevdet Merih
AU - Bar-Oz, Guy
AU - Pompanon, François
AU - Cumer, Tristan
AU - Çakırlar, Canan
AU - Mohaseb, Azadeh Fatemeh
AU - Decruyenaere, Delphine
AU - Davoudi, Hossein
AU - Çevik, Özlem
AU - Rollefson, Gary
AU - Vigne, Jean Denis
AU - Khazaeli, Roya
AU - Fathi, Homa
AU - Doost, Sanaz Beizaee
AU - Sorkhani, Roghayeh Rahimi
AU - Vahdati, Ali Akbar
AU - Sauer, Eberhard W.
AU - Kharanaghi, Hossein Azizi
AU - Maziar, Sepideh
AU - Gasparian, Boris
AU - Pinhasi, Ron
AU - Martin, Louise
AU - Orton, David
AU - Arbuckle, Benjamin S.
AU - Benecke, Norbert
AU - Manica, Andrea
AU - Horwitz, Liora Kolska
AU - Mashkour, Marjan
AU - Bradley, Daniel G.
N1 - Funding Information:
Supported by ERC Investigator grant 295729-CodeX. Additional support from Science Foundation Ireland Award 12/ERC/B2227. P.M.D. was supported by the HERA Joint Research Programme “Uses of the Past” (CitiGen); and the European Union’s Horizon 2020 research and innovation program under grant agreement no. 649307. A.M. was supported by ERC Consolidator grant 647787-LocalAdaptation. M.D.T. was supported by the Marie Skłodowska-Curie Individual Fellowship SCRIBE H2020-MSCA-IF-2016 747424.
Publisher Copyright:
2017 © The Authors.
PY - 2018/7/6
Y1 - 2018/7/6
N2 - Current genetic data are equivocal as to whether goat domestication occurred multiple times or was a singular process. We generated genomic data from 83 ancient goats (51 with genome-wide coverage) from Paleolithic to Medieval contexts throughout the Near East. Our findings demonstrate that multiple divergent ancient wild goat sources were domesticated in a dispersed process that resulted in genetically and geographically distinct Neolithic goat populations, echoing contemporaneous human divergence across the region. These early goat populations contributed differently to modern goats in Asia, Africa, and Europe. We also detect early selection for pigmentation, stature, reproduction, milking, and response to dietary change, providing 8000-year-old evidence for human agency in molding genome variation within a partner species.
AB - Current genetic data are equivocal as to whether goat domestication occurred multiple times or was a singular process. We generated genomic data from 83 ancient goats (51 with genome-wide coverage) from Paleolithic to Medieval contexts throughout the Near East. Our findings demonstrate that multiple divergent ancient wild goat sources were domesticated in a dispersed process that resulted in genetically and geographically distinct Neolithic goat populations, echoing contemporaneous human divergence across the region. These early goat populations contributed differently to modern goats in Asia, Africa, and Europe. We also detect early selection for pigmentation, stature, reproduction, milking, and response to dietary change, providing 8000-year-old evidence for human agency in molding genome variation within a partner species.
UR - http://www.scopus.com/inward/record.url?scp=85049885349&partnerID=8YFLogxK
U2 - 10.1126/science.aas9411
DO - 10.1126/science.aas9411
M3 - Article
C2 - 29976826
AN - SCOPUS:85049885349
SN - 0036-8075
VL - 361
SP - 85
EP - 88
JO - Science
JF - Science
IS - 6397
ER -
