Anal human papillomavirus and HIV: A cross-sectional study among men who have sex with men in Moscow, Russia, 2012–2013

A. L. Wirtz; C. E. Zelaya; A. Peryshkina; I. McGowan; R. D. Cranston; C. Latkin; N. Galai; V. Mogilniy; P. Dzhigun; I. Kostetskaya; C. Beyrer

doi:10.2807/1560-7917.es2015.20.15.21095

Anal human papillomavirus and HIV: A cross-sectional study among men who have sex with men in Moscow, Russia, 2012–2013

A. L. Wirtz, C. E. Zelaya, A. Peryshkina, I. McGowan, R. D. Cranston, C. Latkin, N. Galai, V. Mogilniy, P. Dzhigun, I. Kostetskaya, C. Beyrer

Research output: Contribution to journal › Article › peer-review

Abstract

Anal human papillomavirus (HPV) is prevalent among men who have sex with men (MSM), but has not been studied in the Russian Federation. A cross-sectional survey and HPV genotyping were conducted among HIV seropositive (n=58) and seronegative MSM (n=65) in Moscow. Multivariable logistic regression was performed to identify correlates of infection with onco-genic HPV genotypes 16 and/or 18 (HPV 16/18). Forty per cent (49/124) of all MSM were infected with at least one anal HPV genotype, 31.5% (39/124) had HPV16/18, and 11.5% (14/121) had high-grade squamous intraepi-thelial lesions (HSIL). HPV 16/18 was more prevalent in HIV seropositive than seronegative men (24/58, 41.4% vs 15/65, 23.1%; p=0.03). HIV infection was independently associated with HPV 16/18 (adjusted odds ratio (AOR): 5.08; 95% confidence intervals (CI): 1.49–17.34, p=0.01), as was having 2–4 steady male sex partners in the last year (vs ≤ 1 partner; AOR: 6.99; 95%CI: 1.94–25.24, p<0.01). History of prison/detention, migration to/within Russia and use of incompatible lubricants were marginally associated with HPV 16/18 (p<0.10). Comprehensive prevention options are needed to address HIV and HPV infection among MSM in Russia and may benefit from inclusion of young men in piloted HPV vaccination programmes.

Original language	English
Pages (from-to)	1-10
Number of pages	10
Journal	Eurosurveillance
Volume	20
Issue number	15
DOIs	https://doi.org/10.2807/1560-7917.es2015.20.15.21095
State	Published - 2015
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2015, European Centre for Disease Prevention and Control (ECDC). All rights reserved.

ASJC Scopus subject areas

Epidemiology
Public Health, Environmental and Occupational Health
Virology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.2807/1560-7917.es2015.20.15.21095

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Wirtz, A. L., Zelaya, C. E., Peryshkina, A., McGowan, I., Cranston, R. D., Latkin, C., Galai, N., Mogilniy, V., Dzhigun, P., Kostetskaya, I., & Beyrer, C. (2015). Anal human papillomavirus and HIV: A cross-sectional study among men who have sex with men in Moscow, Russia, 2012–2013. Eurosurveillance, 20(15), 1-10. https://doi.org/10.2807/1560-7917.es2015.20.15.21095

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abstract = "Anal human papillomavirus (HPV) is prevalent among men who have sex with men (MSM), but has not been studied in the Russian Federation. A cross-sectional survey and HPV genotyping were conducted among HIV seropositive (n=58) and seronegative MSM (n=65) in Moscow. Multivariable logistic regression was performed to identify correlates of infection with onco-genic HPV genotypes 16 and/or 18 (HPV 16/18). Forty per cent (49/124) of all MSM were infected with at least one anal HPV genotype, 31.5% (39/124) had HPV16/18, and 11.5% (14/121) had high-grade squamous intraepi-thelial lesions (HSIL). HPV 16/18 was more prevalent in HIV seropositive than seronegative men (24/58, 41.4% vs 15/65, 23.1%; p=0.03). HIV infection was independently associated with HPV 16/18 (adjusted odds ratio (AOR): 5.08; 95% confidence intervals (CI): 1.49–17.34, p=0.01), as was having 2–4 steady male sex partners in the last year (vs ≤ 1 partner; AOR: 6.99; 95%CI: 1.94–25.24, p<0.01). History of prison/detention, migration to/within Russia and use of incompatible lubricants were marginally associated with HPV 16/18 (p<0.10). Comprehensive prevention options are needed to address HIV and HPV infection among MSM in Russia and may benefit from inclusion of young men in piloted HPV vaccination programmes.",

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AU - Peryshkina, A.

AU - McGowan, I.

AU - Cranston, R. D.

AU - Latkin, C.

AU - Galai, N.

AU - Mogilniy, V.

AU - Dzhigun, P.

AU - Kostetskaya, I.

AU - Beyrer, C.

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Anal human papillomavirus and HIV: A cross-sectional study among men who have sex with men in Moscow, Russia, 2012–2013

Abstract

Bibliographical note

ASJC Scopus subject areas

UN SDGs

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