An analytical contrast between fitness maximization and selection for mixability

Adi Livnat, Christos Papadimitriou, Marcus W. Feldman

Research output: Contribution to journalLetterpeer-review


It has been recently shown numerically that sex enables selection for alleles that perform well across different genetic contexts, i.e., selection for mixability. Here we capture this result analytically in a simple case. This serves a dual purpose. First, it provides a clear distinction between fitness maximization and selection for mixability. Second, it points out a limitation of the traditional analytical approach as applied to mixability.

Original languageEnglish
Pages (from-to)232-234
Number of pages3
JournalJournal of Theoretical Biology
Issue number1
StatePublished - 21 Mar 2011
Externally publishedYes

Bibliographical note

Funding Information:
A.L. acknowledges financial support from the Miller Institute for Basic Research in Science. Research supported in part by NSF Grant CCF-0635319 to CP and NIH grant GM28016 to MWF.


  • Evolutionary transient
  • Linear dynamics
  • Recombination
  • Sex
  • Symmetric fitness model

ASJC Scopus subject areas

  • Statistics and Probability
  • Modeling and Simulation
  • General Biochemistry, Genetics and Molecular Biology
  • General Immunology and Microbiology
  • General Agricultural and Biological Sciences
  • Applied Mathematics


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