Alternatively spliced Spalax heparanase inhibits extracellular matrix degradation, tumor growth, and metastasis

Keyphrases

• Adaptation 10%
• Alternative Splicing 100%
• Angiogenesis 10%
• Anticancer Drugs 10%
• Blind Mole Rat 10%
• Cancer Cells 10%
• Cell Surface 10%
• Dominant Negative 10%
• Endoglycosidase 10%
• Enzymatic Activity 20%
• Exon 3 10%
• Exon 4 10%
• Exon 5 10%
• Exon 6 10%
• Exon 7 10%
• Extracellular Matrix 10%
• Extracellular Matrix Degradation 100%
• Glioma Growth 10%
• Heparan Sulfate 20%
• Heparanase 100%
• Lung Colonization 10%
• Mouse Model 10%
• Normoxic 10%
• Skipping 20%
• Spalax 100%
• Splice Variant 30%
• Splicing Model 10%
• Subterranean Environment 10%
• Therapeutic Modalities 10%
• Tumor Aggressiveness 10%
• Tumor Angiogenesis 20%
• Tumor Growth 100%
• Tumor Metastasis 100%

Biochemistry, Genetics and Molecular Biology

• Alternative Splicing 10%
• Angiogenesis 30%
• Anticancer 10%
• Cancer Cell 10%
• Endoglycosidase 10%
• Enzyme 10%
• Enzyme Activity 20%
• Exon 40%
• Heparan Sulfate 20%
• Heparanase 100%
• Mouse Model 10%
• Spalax 100%
• Surface Property 10%
• Tumor Progression 100%
• Wild Type 10%