Alterations in R-R variability associated with experimental motion sickness

Ilana Doweck, Carlos R. Gordon, Arie Shlitner, Orna Spitzer, Adi Gonen, Ofer Binah, Yehuda Melamed, Avi Shupak

Research output: Contribution to journalArticlepeer-review

Abstract

Motion sickness is a complex integration of responses from multiple physiological systems. Whether the changes that occur during the time course of motion sickness are mediated by the sympathetic or parasympathetic systems is still controversial. The present study evaluates alterations in R-R variability during experimental motion sickness in motion sick and non-motion sick subjects. Ten motion sick subjects and 7 non-motion sick subjects participated in the study. Power spectrum analysis of R-R variation was conducted for all subjects 10 min before a brief vestibular disorientation test (BVDT), for 5-10 min of the test, and 10 min after the test. Subjects were also asked to report their symptoms during the test. The motion sick group showed a significant reduction in the power spectrum density of the R-R interval at the mid and high frequencies during the BVDT test period (BVDT), in comparison with the rest period (Rest). These changes probably indicate a decrease in parasympathetic activity during the time course of motion sickness. The non-motion sick group did not show significant differences at any of the frequencies during BVDT. Power spectrum analysis of the R-R interval provides an objective measure of the autonomic response to experimental motion sickness.

Original languageEnglish
Pages (from-to)31-37
Number of pages7
JournalJournal of the Autonomic Nervous System
Volume67
Issue number1-2
DOIs
StatePublished - 3 Dec 1997
Externally publishedYes

Keywords

  • Autonomic function
  • Motion sickness
  • R-R variability

ASJC Scopus subject areas

  • Clinical Neurology
  • Physiology
  • General Neuroscience

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