Adherence and retention of female injection drug users in a phase III clinical trial in inner city Baltimore

Richard D. Semba; Erin P. Ricketts; Shruti F. Mehta; Gregory D. Kirk; Carl Latkin; Noya Galai; David Vlahov

doi:10.1080/00952990601082696

Adherence and retention of female injection drug users in a phase III clinical trial in inner city Baltimore

Richard D. Semba
, Erin P. Ricketts
, Shruti F. Mehta
, Gregory D. Kirk
, Carl Latkin
, Noya Galai
, David Vlahov

Department of Statistics

Research output: Contribution to journal › Article › peer-review

Abstract

Adherence and retention of female injection drug users (IDUs) in clinical trials are not well known and were evaluated among 458 female IDUs in a clinical trial in Baltimore. Of all, 62.9% were adherent to visits (attended ≥ 80% of visits). Of women with ≥ 1 visit after enrollment, 76% were adherent to treatment (took ≥ 80% of pills); 27.7% were lost to follow-up (missed ≥ 3 consecutive visits). Women nonadherent to visits were younger and less likely to be on methadone. Women lost to follow-up were younger, more often white, not on methadone, and injecting drugs daily. Fair-moderate adherence to visits and treatment occurs among female IDUs in a clinical trial.

Original language	English
Pages (from-to)	71-80
Number of pages	10
Journal	American Journal of Drug and Alcohol Abuse
Volume	33
Issue number	1
DOIs	https://doi.org/10.1080/00952990601082696
State	Published - Jan 2007

Bibliographical note

Funding Information:
This study was supported by the National Institute on Nursing Research (R01 NR009478) and the National Institute on Drug Abuse (R01 DA15022).

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Adherence
Clinical trial
HCV
HIV
Injection drug user
Minority

ASJC Scopus subject areas

Medicine (miscellaneous)
Clinical Psychology
Psychiatry and Mental health

Access to Document

10.1080/00952990601082696

Cite this

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title = "Adherence and retention of female injection drug users in a phase III clinical trial in inner city Baltimore",

abstract = "Adherence and retention of female injection drug users (IDUs) in clinical trials are not well known and were evaluated among 458 female IDUs in a clinical trial in Baltimore. Of all, 62.9\% were adherent to visits (attended ≥ 80\% of visits). Of women with ≥ 1 visit after enrollment, 76\% were adherent to treatment (took ≥ 80\% of pills); 27.7\% were lost to follow-up (missed ≥ 3 consecutive visits). Women nonadherent to visits were younger and less likely to be on methadone. Women lost to follow-up were younger, more often white, not on methadone, and injecting drugs daily. Fair-moderate adherence to visits and treatment occurs among female IDUs in a clinical trial.",

keywords = "Adherence, Clinical trial, HCV, HIV, Injection drug user, Minority",

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note = "Funding Information: This study was supported by the National Institute on Nursing Research (R01 NR009478) and the National Institute on Drug Abuse (R01 DA15022).",

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doi = "10.1080/00952990601082696",

language = "English",

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AU - Semba, Richard D.

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AU - Mehta, Shruti F.

AU - Kirk, Gregory D.

AU - Latkin, Carl

AU - Galai, Noya

AU - Vlahov, David

N1 - Funding Information: This study was supported by the National Institute on Nursing Research (R01 NR009478) and the National Institute on Drug Abuse (R01 DA15022).

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AB - Adherence and retention of female injection drug users (IDUs) in clinical trials are not well known and were evaluated among 458 female IDUs in a clinical trial in Baltimore. Of all, 62.9% were adherent to visits (attended ≥ 80% of visits). Of women with ≥ 1 visit after enrollment, 76% were adherent to treatment (took ≥ 80% of pills); 27.7% were lost to follow-up (missed ≥ 3 consecutive visits). Women nonadherent to visits were younger and less likely to be on methadone. Women lost to follow-up were younger, more often white, not on methadone, and injecting drugs daily. Fair-moderate adherence to visits and treatment occurs among female IDUs in a clinical trial.

KW - Adherence

KW - Clinical trial

KW - HCV

KW - HIV

KW - Injection drug user

KW - Minority

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ER -

Adherence and retention of female injection drug users in a phase III clinical trial in inner city Baltimore

Abstract

Bibliographical note

UN SDGs

Keywords

ASJC Scopus subject areas

Access to Document

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Cite this