Acetaminophen hepatotoxicity and mechanisms of its protection by N-acetylcysteine: A study of Hep3B cells

Keyphrases

• N-acetylcysteine 100%
• Acetaminophen Hepatotoxicity 100%
• Acetaminophen 100%
• Hep3B Cells 100%
• Apoptosis 57%
• Oxidative Damage 42%
• Cytotoxicity 28%
• Cell Death 14%
• Reactive Oxygen Species 14%
• Early Events 14%
• Oxidative Stress 14%
• Induced Apoptosis 14%
• Cytotoxic Effect 14%
• Molecular Sequencing 14%
• Excessive Use 14%
• Mitochondrial Dysfunction 14%
• Cell Viability 14%
• Flow Cytometry 14%
• Suicidal Attempt 14%
• Transmission Electron Microscopy 14%
• Concentration-dependent 14%
• Glutathione 14%
• Reactive Oxygen Species Production 14%
• LDH Leakage 14%
• Hep3B 14%
• Hepatoblastoma 14%
• Alamar Blue 14%
• Membrane Permeability 14%
• Flow Transmission 14%
• Reduction Test 14%
• Protective Agents 14%
• Glutathione Depletion 14%
• Centrilobular Necrosis 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Paracetamol 100%
• Hepatotoxicity 100%
• Acetylcysteine 100%
• Cytotoxicity 30%
• Lactate Dehydrogenase 20%
• Reactive Oxygen Metabolite 20%
• Glutathione 20%
• Cell Viability 10%
• Liver Cell Carcinoma 10%
• Flow Cytometry 10%
• Necrosis 10%
• Protective Agent 10%
• Transmission Electron Microscopy 10%

Immunology and Microbiology

• Programmed Cell Death 100%
• Cytotoxicity 60%
• Glutathione 40%
• Cell Death 20%
• Oxidative Stress 20%
• Transmission Electron Microscopy 20%
• Cell Viability 20%
• Membrane Permeability 20%
• Adolescence 20%