A naturalistic study on ending blind dosing in a methadone maintenance clinic in Israel

Avi Bleich, Marc Gelkopf, Rachel Hayward, Miriam Adelson

Research output: Contribution to journalArticlepeer-review


Since many methadone maintenance treatment (MMT) clinics in the United States do not share with patients, information concerning their methadone dosage, we aimed to investigate the impact of patients being informed of their methadone dosage and the influence of ending blind dosing on treatment outcome. Seventy-four patients who were unaware of their methadone dosage took part in this study. We compared changes in opiate abuse, levels of methadone dosage and patients' perceptions of dosage adequacy before and after they were informed of their dosage. Data on opiate abuse were based upon bi-weekly randomly taken and observed urine tests provided the data on opiate abuse. Records on methadone dosage were kept and a short questionnaire on dosage-related attitudes, devised for this study, was administered. Most patients expressed the desire to know their dosage, but there were no significant changes in opiate abuse, methadone dosage or the patients' perceptions of dosage adequacy after they knew what it was. We conclude that informing patients of their methadone dosage and thereby ending blind dosing does not seem to have any negative effect on treatment outcomes. We believe that this policy is in accord with the patients' rights and expressed will to know their dosage and this justifies putting an end to blind dosing policies.

Original languageEnglish
Pages (from-to)191-194
Number of pages4
JournalDrug and Alcohol Dependence
Issue number2
StatePublished - 1 Jan 2001
Externally publishedYes


  • Blind dosing
  • Candor
  • Clinic policy
  • Drug dependence
  • Medical ethics
  • Methadone maintenance
  • Patient-therapist relationship

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Pharmacology (medical)
  • Toxicology
  • Pharmacology


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