A kinase-START gene confers temperature-dependent resistance to wheat stripe rust

Daolin Fu, Cristobal Uauy, Assaf Distelfeld, Ann Blechl, Lynn Epstein, Xianming Chen, Hanan Sela, Tzion Fahima, Jorge Dubcovsky

Research output: Contribution to journalArticlepeer-review


Stripe rust is a devastating fungal disease that afflicts wheat in many regions of the world. New races of Puccinia striiformis, the pathogen responsible for this disease, have overcome most of the known race-specific resistance genes. We report the map-based cloning of the gene Yr36 (WKS1), which confers resistance to a broad spectrum of stripe rust races at relatively high temperatures (25° to 35°C). This gene includes a kinase and a putative START lipid-binding domain. Five independent mutations and transgenic complementation confirmed that both domains are necessary to confer resistance. Yr36 is present in wild wheat but is absent in modern pasta and bread wheat varieties, and therefore it can now be used to improve resistance to stripe rust in a broad set of varieties.

Original languageEnglish
Pages (from-to)1357-1360
Number of pages4
Issue number5919
StatePublished - 2009

ASJC Scopus subject areas

  • General


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