Research output per year
Research output per year
- 30 results
Search results
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2023
Damage-Free Shortening of Telomeres Is a Potential Strategy Supporting Blind Mole-Rat Longevity
Adwan Shekhidem, H., Sharvit, L., Huffman, D. M., Manov, I., Atzmon, G. & Shams, I., 31 Mar 2023, In: Genes. 14, 4, 845.Research output: Contribution to journal › Article › peer-review
Open Access -
Senescent Secretome of Blind Mole Rat Spalax Inhibits Malignant Behavior of Human Breast Cancer Cells Triggering Bystander Senescence and Targeting Inflammatory Response
Odeh, A., Eddini, H., Shawasha, L., Chaban, A., Avivi, A., Shams, I. & Manov, I., 7 Mar 2023, In: International Journal of Molecular Sciences. 24, 6, 5132.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Aging without inflammaging: Lesson from Spalax
Manov, I., Odeh, A. & Shams, I., 27 Aug 2020, In: Aging. 12, 16, p. 15875-15877 3 p.Research output: Contribution to journal › Editorial
Open Access -
Downregulation of the inflammatory network in senescent fibroblasts and aging tissues of the long-lived and cancer-resistant subterranean wild rodent, Spalax
Odeh, A., Dronina, M., Domankevich, V., Shams, I. & Manov, I., 1 Jan 2020, In: Aging Cell. 19, 1, e13045.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Telomeres and longevity: A cause or an effect?
Shekhidem, H. A., Sharvit, L., Leman, E., Manov, I., Roichman, A., Holtze, S., Huffman, D. M., Cohen, H. Y., Hildebrandt, T. B., Shams, I. & Atzmon, G., 1 Jul 2019, In: International Journal of Molecular Sciences. 20, 13, 3233.Research output: Contribution to journal › Article › peer-review
Open Access -
The transcriptome landscape of the carcinogenic treatment response in the blind mole rat: Insights into cancer resistance mechanisms
Altwasser, R., Paz, A., Korol, A., Manov, I., Avivi, A. & Shams, I., 8 Jan 2019, In: BMC Genomics. 20, 1, 17.Research output: Contribution to journal › Article › peer-review
Open Access -
2018
Adipose-Derived Stem Cells of Blind Mole Rat Spalax Exhibit Reduced Homing Ability: Molecular Mechanisms and Potential Role in Cancer Suppression
Mamchur, A., Leman, E., Salah, S., Avivi, A., Shams, I. & Manov, I., Oct 2018, In: Stem Cells. 36, 10, p. 1630-1642 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2016
Adaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat Spalax
Domankevich, V., Opatowsky, Y., Malik, A., Korol, A. B., Frenkel, Z., Manov, I., Avivi, A. & Shams, I., 2 Sep 2016, In: BMC Evolutionary Biology. 16, 1, 177.Research output: Contribution to journal › Article › peer-review
Open Access -
2014
Iron-rich ferritin in the hypoxia-tolerant rodent Spalax ehrenbergi: A naturally-occurring biomarker confirms the internalization and pathways of intracellular macromolecules
Iancu, T. C., Arad, T., Shams, I. & Manov, I., Sep 2014, In: Journal of Structural Biology. 187, 3, p. 254-265 12 p.Research output: Contribution to journal › Article › peer-review
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2013
Effects of novel neuroprotective and neurorestorative multifunctional drugs on iron chelation and glucose metabolism
Pollak, Y., Mechlovich, D., Amit, T., Bar-Am, O., Manov, I., Mandel, S. A., Weinreb, O., Meyron-Holtz, E. G., Iancu, T. C. & Youdim, M. B. H., Jan 2013, In: Journal of Neural Transmission. 120, 1, p. 37-48 12 p.Research output: Contribution to journal › Article › peer-review
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Infantile mitochondrial hepatopathy is a cardinal feature of MEGDEL syndrome (3-Methylglutaconic aciduria type IV with sensorineural deafness, encephalopathy and leigh-Like Syndrome) caused by novel mutations in SERAC1
Sarig, O., Goldsher, D., Nousbeck, J., Fuchs-Telem, D., Cohen-Katsenelson, K., Iancu, T. C., Manov, I., Saada, A., Sprecher, E. & Mandel, H., Sep 2013, In: American Journal of Medical Genetics, Part A. 161, 9, p. 2204-2215 12 p.Research output: Contribution to journal › Article › peer-review
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Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: In vivo and in vitro evidence
Manov, I., Hirsh, M., Iancu, T. C., Malik, A., Sotnichenko, N., Band, M., Avivi, A. & Shams, I., 9 Aug 2013, In: BMC Biology. 11, 91.Research output: Contribution to journal › Article › peer-review
Open Access -
Transcription pattern of p53-targeted DNA repair genes in the hypoxia-tolerant subterranean mole rat Spalax
Shams, I., Malik, A., Manov, I., Joel, A., Band, M. & Avivi, A., 12 Apr 2013, In: Journal of Molecular Biology. 425, 7, p. 1111-1118 8 p.Research output: Contribution to journal › Article › peer-review
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What's in a Name?-Lipolysosome: Ultrastructural features of a lipid-containing organelle
Iancu, T. C., Manov, I., Shaoul, R., Haimi, M. & Lerner, A., Oct 2013, In: Ultrastructural Pathology. 37, 5, p. 293-303 11 p.Research output: Contribution to journal › Article › peer-review
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2012
Poor lysosomal membrane integrity in proximal tubule cells of haptoglobin 2-2 genotype mice with diabetes mellitus
Asleh, R., Nakhoul, F. M., Miller-Lotan, R., Awad, H., Farbstein, D., Levy, N. S., Nakhoul, N., Iancu, T. C., Manov, I., Laue, M., Traber, M. G., Lebold, K. M. & Levy, A. P., 15 Aug 2012, In: Free Radical Biology and Medicine. 53, 4, p. 779-786 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2011
Inhibition of doxorubicin-induced autophagy in hepatocellular carcinoma Hep3B cells by sorafenib - The role of extracellular signal-regulated kinase counteraction
Manov, I., Pollak, Y., Broneshter, R. & Iancu, T. C., Sep 2011, In: FEBS Journal. 278, 18, p. 3494-3507 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2010
Ultrastructural aspects of enterocyte defects in infancy and childhood
Iancu, T. C. & Manov, I., 2010, In: Ultrastructural Pathology. 34, 3, p. 117-125 9 p.Research output: Contribution to journal › Article › peer-review
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2008
Monoubiquitylation of α-Synuclein by seven in absentia homolog (SIAH) promotes its aggregation in dopaminergic cells
Rott, R., Szargel, R., Haskin, J., Shani, V., Shainskaya, A., Manov, I., Liani, E., Avraham, E. & Engelender, S., 8 Feb 2008, In: Journal of Biological Chemistry. 283, 6, p. 3316-3328 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2007
A Newborn Infant with Protracted Diarrhea and Metabolic Acidosis
Bar, A., Riskin, A., Iancu, T., Manov, I., Arad, A. & Shaoul, R., Feb 2007, In: Journal of Pediatrics. 150, 2, p. 198-201 4 p.Research output: Contribution to journal › Article › peer-review
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High-dose acetaminophen inhibits the lethal effect of doxorubicin in HepG2 cells: The role of P-glycoprotein and mitogen-activated protein kinase p44/42 pathway
Manov, I., Bashenko, Y., Eliaz-Wolkowicz, A., Mizrahi, M., Liran, O. & Iancu, T. C., Sep 2007, In: Journal of Pharmacology and Experimental Therapeutics. 322, 3, p. 1013-1022 10 p.Research output: Contribution to journal › Article › peer-review
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Microvillous inclusion disease: Ultrastructural variability
Iancu, T. C., Mahajnah, M., Manov, I. & Shaoul, R., Jun 2007, In: Ultrastructural Pathology. 31, 3, p. 173-188 16 p.Research output: Contribution to journal › Article › peer-review
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The liver in congenital disorders of glycosylation: Ultrastructural features
Iancu, T. C., Mahajnah, M., Manov, I., Cherurg, S., Knopf, C. & Mandel, H., Jun 2007, In: Ultrastructural Pathology. 31, 3, p. 189-197 9 p.Research output: Contribution to journal › Article › peer-review
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Ultrastructural features of lymphocyte suppression induced by anthrax lethal toxin and treated with chloroquine
Hirsh, M. I., Manov, I., Cohen-Kaplan, V. & Iancu, T. C., Feb 2007, In: Laboratory Investigation. 87, 2, p. 182-188 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2006
Hepatotoxicity of anti-inflammatory and analgesic drugs: Ultrastructural aspects
Manov, I., Motanis, H., Frumin, I. & Ciancu, T., Mar 2006, In: Acta Pharmacologica Sinica. 27, 3, p. 259-272 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Involvement of the multidrug resistance P-glycoprotein in acetaminophen-induced toxicity in hepatoma-derived HepG2 and Hep3B cells
Manov, I., Bashenko, Y., Hirsh, M. & Iancu, T. C., Sep 2006, In: Basic and Clinical Pharmacology and Toxicology. 99, 3, p. 213-224 12 p.Research output: Contribution to journal › Article › peer-review
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2004
Human herpesvirus 8 in primary effusion lymphoma in an HIV-seronegative male: A case report
Munichor, M., Cohen, H., Sarid, R., Manov, I. & Iancu, T. C., 2004, In: Acta Cytologica. 48, 3, p. 425-430 6 p.Research output: Contribution to journal › Article › peer-review
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N-acetylcysteine does not protect HepG2 cells against acetaminophen-induced apoptosis
Manov, I., Hirsh, M. & Iancu, T. C., May 2004, In: Basic and Clinical Pharmacology and Toxicology. 94, 5, p. 213-225 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Qualitative and Quantitative Analysis of the Effects of Acetaminophen and N-Acetylcysteine on the Surface Morphology of Hep3B Hepatoma Cells in Vitro
Levanon, D., Manov, I. & Iancu, T. C., 2004, In: Ultrastructural Pathology. 28, 1, p. 3-14 12 p.Research output: Contribution to journal › Article › peer-review
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2002
Acetaminophen hepatotoxicity and mechanisms of its protection by N-acetylcysteine: A study of Hep3B cells
Manov, I., Hirsh, M. & Iancu, T. C., 2002, In: Experimental and Toxicologic Pathology. 53, 6, p. 489-500 12 p.Research output: Contribution to journal › Article › peer-review
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2001
The hepatic mitochondrial DNA depletion syndrome: Ultrastructural changes in liver biopsies
Mandel, H., Hartman, C., Berkowitz, D., Elpeleg, O. N., Manov, I. & Iancu, T. C., 2001, In: Hepatology. 34, 4 I, p. 776-784 9 p.Research output: Contribution to journal › Article › peer-review
Open Access